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NCT05845333
Neurocognitive Abnormalities in Stimulant Abuse Among High-Risk Women
trial testing Decision task in Stimulant Abuse in 334 participants. Currently enrolling.
31 May 2027
Quick facts
| Lead sponsor | The Mind Research Network |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 334 |
| Start date | 1 August 2022 |
| Primary completion | 31 May 2027 |
| Estimated completion | 31 May 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Decision task
Conditions studied
- Stimulant Abuse — all drugs for Stimulant Abuse →
- Criminal Behavior — all drugs for Criminal Behavior →
Sponsor
The Mind Research Network
Who can join
Adults 18 to 70, female only, with Stimulant Abuse or Criminal Behavior. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Substance use disorders and psychopathy are serious and costly mental health issues. Psychopathy is known to be associated with aberrant moral decision making and there is considerable interest in determining whether substance use disorders lead to impairments in these same cognitive processes. Recent large-scale research initiatives in forensic settings have begun to identify substance abuse and psychopathy-related disruption in the neural mechanisms involved in moral decision-making processes, and associations between these neural networks and future relapse and antisocial behavior. Here the investigators extend prior work (with incarcerated men) to examine these issues among incarcerated women in order to better understand sex differences. This project addresses the overall lack of neurocognitive research in criminal offenders with substance use disorders, thereby focusing on a major public health issue in an underserved and understudied population.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05845333 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Mind Research Network
- Last refreshed: 8 May 2025
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing