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NCT05844215
MMP-9, TIMP-9 in Lung Imaging and Functional of COVID-19
trial testing MMP-9 and TIMP-1 in Pulmonary Infection in 78 participants. Completed in 20 July 2022.
24 December 2021
Quick facts
| Lead sponsor | Universitas Airlangga |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 78 |
| Start date | 15 March 2021 |
| Primary completion | 24 December 2021 |
| Estimated completion | 20 July 2022 |
| Sites | 1 location across Indonesia |
Drugs / interventions tested
- MMP-9 and TIMP-1
Conditions studied
- Pulmonary Infection — all drugs for Pulmonary Infection →
- COVID-19 — all drugs for COVID-19 →
- Extracellular Matrix Alteration — all drugs for Extracellular Matrix Alteration →
Sponsor
Universitas Airlangga — full company profile →
Who can join
Adults 21 to 70, any sex, with Pulmonary Infection or COVID-19. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to determine the role of the extracellular matrix in lung abnormalities in COVID-19 patients. Anatomical abnormalities of the lungs can be observed by the presence of abnormalities on a chest x-ray that is scored using the Brixia index. The presence of COVID-19 pneumonia can impact oxygenation disorders. It is hoped that knowing the relationship between biomarkers that affect the extracellular matrix and anatomical and functional abnormalities can open up new insights into new therapeutic opportunities. The balance of MMP-9 and TIMP-1 has been studied in relation to several lung diseases other than COVID-19.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05844215
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05844215 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universitas Airlangga
- Last refreshed: 6 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05844215.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing