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NCT05841121
Antenatal Dexamethasone for Late Preterm Deliveries
Phase 1 trial testing Dexamethasone in Respiratory Distress of Newborn in 294 participants. Status unknown.
28 March 2024
Quick facts
| Lead sponsor | Chulalongkorn University |
|---|---|
| Phase | Phase 1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 294 |
| Start date | 25 August 2023 |
| Primary completion | 28 March 2024 |
| Estimated completion | 30 April 2024 |
| Sites | 1 location across Vietnam |
Drugs / interventions tested
- Dexamethasone (dexamethasone) — full drug profile →
Conditions studied
- Respiratory Distress of Newborn — all drugs for Respiratory Distress of Newborn →
- Preterm Birth — all drugs for Preterm Birth →
Sponsor
Chulalongkorn University
Who can join
Adults 18 to 45, female only, with Respiratory Distress of Newborn or Preterm Birth. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to compare dexamethasone in late preterm deliveries. The main questions it aims to answer are: Does antenatal dexamethasone reduce the need for respiratory support in late preterm infants? Does antenatal dexamethasone reduce neonatal morbidities and mortality? Does antenatal dexamethasone reduce admission to Neonatal Intensive Care Unit and length of hospital stay? Participants will be allocated into 2 groups: intervention with dexamethasone IM and control (standard care). Investigators will compare these two groups to see if antenatal dexamethasone reduces the need for respiratory support in late preterm infants, neonatal morbidities and mortality, admission to NICU and length of hospital stay.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Impact of Antenatal Dexamethasone on Respiratory Outcomes in Late Preterm Infants in a Vietnamese Tertiary Hospital: A Randomised Controlled Trial.
Le CHM, Tran HT, Huynh QK, Chaithongwongwatthana S. · · 2026 · PMID 41452963 · DOI 10.1111/apa.70417
Verify or expand the search:
- PubMed search for NCT05841121
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05841121 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chulalongkorn University
- Last refreshed: 8 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05841121.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing