Last reviewed · How we verify
NCT05840718
Supplemental Thiamine in Septic Shock: A Before-after Study
trial testing Thiamin in Septic Shock in 73 participants. Completed in 31 December 2023.
30 November 2023
Quick facts
| Lead sponsor | Hospital Sao Domingos |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 73 |
| Start date | 1 September 2023 |
| Primary completion | 30 November 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 2 locations across Brazil |
Drugs / interventions tested
- Thiamin — full drug profile →
Conditions studied
- Septic Shock — all drugs for Septic Shock →
Sponsor
Hospital Sao Domingos
Who can join
18 and older, any sex, with Septic Shock. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This controlled before-and-after study analyse the impact of thiamine supplementation on outcomes of patients with septic shock treated according to the surviving sepsis campaign 2021 guidelines
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Impact of thiamine supplementation on mortality in septic shock: a retrospective before-after study
Ribeiro BL, Nascimento CM, Carvalho IM, Gama HLJ, et al · · 2024 · DOI 10.21203/rs.3.rs-3860455/v1
Verify or expand the search:
- PubMed search for NCT05840718
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Septic Shock
Currently open trials in the same condition.
- NCT07179276 — Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock · NA · recruiting
- NCT07383103 — Hydrocortisone and Fludrocortisone for the Treatment of Septic Shock · Phase 4 · recruiting
- NCT07419802 — OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study · recruiting
- NCT07264543 — Early Methylene Blue in the Microhemodynamics of Septic Patients · Phase 2, PHASE3 · recruiting
- NCT04855786 — External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients · NA · recruiting
Other Hospital Sao Domingos trials
Trials by the same sponsor.
- NCT06244381 — Indirect Calorimetry Versus Urea-creatinine Ratio to Evaluate Catabolism in Critically Ill Patients · completed
- NCT05790915 — Impact of Interventions on Admission SOFA Score on Clinical Outcomes of Critically Ill Patients · completed
- NCT05839327 — Impact of Mental Health and Cognitive Disorders on Quality of Life in Severe Covid-19 Survivors · unknown
- NCT05448534 — Electroencephalographic Patterns of Septic Patients and Its Correlation With Cognitive Outcomes · completed
- NCT04454372 — Clinical Characteristics and Outcomes of 187 Critically Ill Patients With Coronavirus Disease 2019 (COVID-19) · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05840718 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Sao Domingos
- Last refreshed: 18 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05840718.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing