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NCT05839821
Rhythmic Auditory Stimulation on Neural Activity During Finger-tapping in PD Patients
trial testing noF-noRAS in Acoustic Stimulation in 72 participants. Status unknown.
31 March 2026
Quick facts
| Lead sponsor | The Hong Kong Polytechnic University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 72 |
| Start date | 1 June 2023 |
| Primary completion | 31 March 2026 |
| Estimated completion | 31 March 2026 |
Drugs / interventions tested
- noF-noRAS
- F-noRAS
- noF-100RAS
- F-100RAS
- F-105RAS
- F-110RAS
Conditions studied
- Acoustic Stimulation — all drugs for Acoustic Stimulation →
- Parkinson Disease — all drugs for Parkinson Disease →
- Electroencephalography — all drugs for Electroencephalography →
Sponsor
The Hong Kong Polytechnic University
Who can join
Adults 18 to 85, any sex, with Acoustic Stimulation or Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction Bradykinesia (i.e., slow movements) is one of the most prominent symptoms of Parkinson's disease (PD) and has a negative impact on quality of life. Rhythmic auditory stimulation (RAS), a widely used and promising treatment technique, has been shown to effectively improve gait speed in PD patients. However, only few studies have explored effects and neural mechanisms of RAS on upper-limb movements. The investigators will conduct two studies to investigate effects and mechanisms of RAS on upper-limb movements in PD patients. The purpose of this study is to examine real-time neural activity when patients with PD and healthy controls listen to RAS and execute finger-tapping task simultaneously. Methods and analysis This study will recruit patients with PD and healthy controls. Electroencephalography (EEG) will be used under six conditions related to a finger-tapping task. Two-way repeated measures analysis of variance will be performed to investigate the group and condition effects on neural mechanisms. Study significance This study will offer evidence on RAS effects and mechanisms by investigating the changes in upper-limb movements and neural mechanisms during auditory-motor entrainment. Results from this study will provide a solid foundation for further research and clinical applications of RAS.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05839821 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Hong Kong Polytechnic University
- Last refreshed: 3 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05839821.
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