Who is sponsoring NCT05836467?

NCT05836467 is sponsored by Michele De Bonis.

What drugs are being tested in NCT05836467?

Interventions in NCT05836467: Valvular interventions.

What condition does NCT05836467 study?

NCT05836467 studies Coronary Artery Disease, Heart Valve Diseases.

Is NCT05836467 still recruiting?

NCT05836467 is currently completed. Last updated 1 May 2023.

Last reviewed 2023-05-01 · How we verify

NCT05836467

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Is Myocardial Revascularization Really Necessary in Patients With ≥50-70% Coronary Stenosis Undergoing Valvular Surgery?

Completed Last updated 1 May 2023

What this trial tests

trial testing Valvular interventions in Coronary Artery Disease in 77 participants. Completed in 15 October 2019.

Timeline

5 October 2019

Primary endpoint
15 October 2019

15 October 2019

Quick facts

Lead sponsor	Michele De Bonis
Status	Completed
Study type	OBSERVATIONAL
Enrollment	77
Start date	5 October 2019
Primary completion	15 October 2019
Estimated completion	15 October 2019
Sites	1 location across Italy

Drugs / interventions tested

Valvular interventions

Conditions studied

Coronary Artery Disease — all drugs for Coronary Artery Disease →
Heart Valve Diseases — all drugs for Heart Valve Diseases →

Sponsor

Michele De Bonis

Who can join

18 and older, any sex, with Coronary Artery Disease or Heart Valve Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is well documented in the literature that myocardial revascularization during valve surgery increases the risk of early mortality and morbidity. According to the most recent version of the European Guidelines, the possibility of myocardial revascularization via coronary artery bypass should be evaluated in patients with an indication for surgical treatment of heart valve disease but with coronary artery stenosis ≥ 50-70%. In this study, patients hospitalized for surgical heart valve disease, with occasional pre-operative finding of ≥ 50-70% coronary artery stenosis, without angina, are examined. After interdisciplinary discussion in the Heart Team, it was decided not to treat coronary artery disease during valve surgery. The aim is to evaluate the short and medium-term results of this "conscious omission".

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Coronary Artery Disease

Currently open trials in the same condition.

NCT07399002 — LONG NAGOMI™ PMCF STUDY · recruiting
NCT07420582 — Antegrade Autologous Blood Reinfusion After CPB · recruiting
NCT07493603 — A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease · Phase 1, PHASE2 · recruiting
NCT06535568 — Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO · NA · recruiting
NCT07286578 — A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Under · NA · recruiting

Other Michele De Bonis trials

Trials by the same sponsor.

NCT05774821 — Surgical Treatment of Tricuspid Valve Regurgitation in Patients With Cardiac Implantable Electronic Devices: Long Term R · completed
NCT05774808 — Fate of Moderate Secondary Mitral Regurgitation in Patients Undergoing Aortic Valve Surgery for Severe Aortic Regurgitat · completed
NCT05721417 — Long-term Outcomes of Isolated Tricuspid Valve Surgery According to Preoperative Clinical and Functional Staging · completed
NCT05774769 — Commissural Closure to Treat Severe Mitral Regurgitation: Standing the Test of Time. · completed
NCT05733988 — Edge-To-Edge Technique Used as a Bailout in Case of Sub-Optimal Mitral Repair: Very Long-Term Results · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05836467 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Michele De Bonis
Last refreshed: 1 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05836467.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing