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NCT05836428
Biomarker Analysis in Post-COVID Patients
trial testing no intervention in Post-COVID-19 Syndrome in 48 participants. Completed in 26 April 2023.
26 April 2023
Quick facts
| Lead sponsor | University Hospital, Bonn |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 48 |
| Start date | 1 August 2020 |
| Primary completion | 26 April 2023 |
| Estimated completion | 26 April 2023 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- no intervention
Conditions studied
- Post-COVID-19 Syndrome — all drugs for Post-COVID-19 Syndrome →
Sponsor
University Hospital, Bonn
Who can join
Adults 18 to 80, any sex, with Post-COVID-19 Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Headache is one of the most common neurological manifestations of COVID-19. However, it is unclear whether chronic headache after the initial diagnosis, is associated with ongoing damage of the central nervous system. We investigate cpost-COVID-19 patients with persistent headache lasting longer than 3 weeks, to hospitalized acute COVID-19 patients with neurological symptoms and to other non-COVID-19 disease-controls. Readout are neurologial and glial biomarkers in CSF.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
No evidence for neuronal damage or astrocytic activation in cerebrospinal fluid of Neuro-COVID-19 patients with long-term persistent headache.
de Boni L, Odainic A, Gancarczyk N, Kaluza L, et al · · 2023 · cited 2× · PMID 37759276 · DOI 10.1186/s42466-023-00277-1
Verify or expand the search:
- PubMed search for NCT05836428
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University Hospital, Bonn trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05836428 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Bonn
- Last refreshed: 1 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05836428.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing