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NCT05834894: MEMO

Does Muscle Mass At Intensive Care Unit Admission Determine Mortality: the Memo Study

Active, enrolled Last updated 6 December 2024
What this trial tests

trial testing exposure(s) of interest : intensive care unit in Lean Body Mass in 4,000 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
1 January 2010
Primary endpoint
31 May 2025
31 October 2025

Quick facts

Lead sponsorUniversity Hospital, Geneva
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment4,000
Start date1 January 2010
Primary completion31 May 2025
Estimated completion31 October 2025
Sites1 location across Switzerland

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Geneva

Who can join

18 and older, any sex, with Lean Body Mass. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This retrospective monocentric study aims to investigate whether a low muscle mass at ICU admission and its loss over the ICU stay predicts mortality, and in what proportion we can counteract it by nutritional support.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Exploring the association between computed tomography (CT)-derived skeletal muscle mass and short- and long-term mortality in critically ill patients: a systematic review and meta-analysis.
    Bertoni Maluf VA, Herrmann FR, Platon A, Mendes A, et al · · 2025 · cited 3× · PMID 40462133 · DOI 10.1186/s13054-025-05427-2
  2. Obesity is associated with lower 30-day mortality in critically ill patients: A retrospective study of over 5400 patients.
    Genton L, Bertoni Maluf VA, Herrmann FR, Prado CM, et al · · 2025 · cited 1× · PMID 40602605 · DOI 10.1016/j.clnesp.2025.06.046

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Other University Hospital, Geneva trials

Trials by the same sponsor.

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