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NCT05834010: ReBoot

Feasibility Study of Using Fecal Microbiota Transplants in Anorexia Nervosa

Completed EARLY_PHASE1 Last updated 27 June 2025
What this trial tests

EARLY_PHASE1 trial testing Fecal Microbiome Transplant in Anorexia Nervosa in 17 participants. Completed in 1 January 2025.

Timeline
18 March 2023
Primary endpoint
1 January 2025
1 January 2025

Quick facts

Lead sponsorHvidovre University Hospital
PhaseEARLY_PHASE1
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposebasic science
Enrollment17
Start date18 March 2023
Primary completion1 January 2025
Estimated completion1 January 2025
Sites3 locations across Denmark

Drugs / interventions tested

Conditions studied

Sponsor

Hvidovre University Hospital

Who can join

18 and older, female only, with Anorexia Nervosa or Microbiome Dysbiosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators hypothesize that prolonged undernutrition in anorexia nervosa alters the microbiome to a different steady-state (dysbiotic) composition that sustains the disease, even after returning to normal diet. The investigators propose that transplanting a fully ecologically functioning GM from a healthy donor, through a FMT, can reboot the gut-brain-axis, ameliorate symptoms and improve clinical outcomes. To approach this, in the challenging AN patient group, the investigators want to conduct a FMT feasibility/pilot study.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Impact of a single fecal microbiome transplantation in adult women with anorexia nervosa: an open-label feasibility pilot trial.
    Panah FM, Støving RK, Sjögren M, Micali N, et al · · 2026 · PMID 41535289 · DOI 10.1038/s41467-026-68455-8

Verify or expand the search:

Other recruiting trials for Anorexia Nervosa

Currently open trials in the same condition.

Other Hvidovre University Hospital trials

Trials by the same sponsor.

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Data sources for this page

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