Last reviewed · How we verify
NCT05828446: AMRIK
Improving Hepatocellular Carcinoma Screening
NA trial testing MRI in Magnetic Resonance Imaging in 330 participants. Currently enrolling.
30 April 2026
Quick facts
| Lead sponsor | Naik Vietti Violi |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | screening |
| Enrollment | 330 |
| Start date | 1 April 2023 |
| Primary completion | 30 April 2026 |
| Estimated completion | 30 April 2027 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- MRI — full drug profile →
Conditions studied
- Magnetic Resonance Imaging — all drugs for Magnetic Resonance Imaging →
- Hepatocellular Carcinoma — all drugs for Hepatocellular Carcinoma →
- Screening — all drugs for Screening →
- Contrast-enhanced US — all drugs for Contrast-enhanced US →
Sponsor
Naik Vietti Violi
Who can join
18 and older, any sex, with Magnetic Resonance Imaging or Hepatocellular Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a monocentric, single blind, interventional, single arm study. It is designed to compare the rates of detection of hepatocellular carcinoma (HCC) by ultrasound (US) used in clinical routine vs. abbreviated magnetic resonance imaging (AMRI). The hypothesis is that dynamic AMRI with extracellular contrast agent injection has a higher patient-level detection rate of HCC than screening US and non-contrast AMRI. Interested and eligible patients will be enrolled and undergo HCC screening rounds including US +/- contrast-enhanced US (clinical routine) and screening MRI within the same week bi-annually.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Recent advances and issues in imaging modalities for hepatocellular carcinoma surveillance.
Lee DH. · · 2025 · cited 5× · PMID 40007309 · DOI 10.17998/jlc.2025.02.16 -
Persisting challenges in the early detection of hepatocellular carcinoma.
Arvind A, Redmon K, Singal AG. · · 2025 · cited 3× · PMID 39943795 · DOI 10.1080/14737140.2025.2467184 -
Abbreviated MRI-Based Surveillance Strategies for Early Hepatocellular Carcinoma Detection.
Park HJ, Kim DW, Choi WM, Kim SY. · · 2025 · cited 1× · PMID 40502477 · DOI 10.3348/jksr.2024.0153
Verify or expand the search:
- PubMed search for NCT05828446
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of MRI
Trials testing the same drug.
- NCT02831335 — Technical Development of Multi-Parametric Renocerebral MRI · recruiting
- NCT07487870 — Radiographic Evaluation of Tumor Biology During Neoadjuvant Radiotherapy for Sarcoma · NA · not yet recruiting
- NCT07567053 — Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study · NA · not yet recruiting
- NCT07537504 — Language Function Reorganization in Patients With Arteriovenous Malformations · not yet recruiting
- NCT07217990 — Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer · Phase 1, PHASE2 · not yet recruiting
Other recruiting trials for Magnetic Resonance Imaging
Currently open trials in the same condition.
- NCT06725550 — Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0 · NA · recruiting
- NCT07138768 — Role of MRI in the Early Diagnosis and Management of Acute Stroke and Its Impact on Turnaround Time in Emergency Setting · recruiting
- NCT07069452 — Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke · recruiting
- NCT06509087 — The Combined Utility of Angio-CT and MRI in Managing Chronic Musculoskeletal Pain: a Prospective Study to Evaluate the E · recruiting
- NCT06108089 — Novel Hypoxia Imaging for Head and Neck Cancer: Imaging Phenotype for Personalized Treatment · recruiting
Other Naik Vietti Violi trials
Trials by the same sponsor.
- NCT06571981 — Conventional Ultrasound Versus Remote Ultraportable ulTrasound in the Context of Viral Hepatitis · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05828446 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Naik Vietti Violi
- Last refreshed: 3 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05828446.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing