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NCT05828199
The Effect of Intraoperative Infusion of Dexmedetomidine Versus Low Dose Ketamine
Phase 1 trial testing Ketamine Hydrochloride in Nasal Polyps in 80 participants. Status unknown.
1 December 2023
Quick facts
| Lead sponsor | Al-Azhar University |
|---|---|
| Phase | Phase 1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 1 December 2022 |
| Primary completion | 1 December 2023 |
| Estimated completion | 20 December 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Ketamine Hydrochloride — full drug profile →
- Dexmedetomidine (dexmedetomidine) — full drug profile →
Conditions studied
- Nasal Polyps — all drugs for Nasal Polyps →
- Nasal Septum, Irregular — all drugs for Nasal Septum, Irregular →
- Functional Endoscopic Sinus Surgery — all drugs for Functional Endoscopic Sinus Surgery →
Sponsor
Al-Azhar University
Who can join
Adults 21 to 40, any sex, with Nasal Polyps or Nasal Septum, Irregular. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Comparing between dexmedetomidine versus low dose ketamine infusion in patients undergoing nasal and paranasal sinus surgery as regard, intraoperative hemodynamic stability, blood loss, perioperative opioid requirements, Stress response evaluation through the measurement of serum level of cortisol, IL-6, blood glucose and CRP.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05828199
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Nasal Polyps
Currently open trials in the same condition.
- NCT07245329 — Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal Polyps · NA · recruiting
- NCT07268313 — Complete Remission After Treatment With Biologics for Nasal Polyps · Phase 4 · recruiting
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Other Al-Azhar University trials
Trials by the same sponsor.
- NCT06489327 — Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery · NA · recruiting
- NCT07327918 — Effect of Epidural Needle Injection on Catheter Placement Success During Painless Labour · Phase 3 · not yet recruiting
- NCT07500194 — Quad Helix vs RME for Posterior Cross-bite in Egyptian Children · NA · not yet recruiting
- NCT07360756 — Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05828199 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Al-Azhar University
- Last refreshed: 25 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05828199.
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