Last reviewed · How we verify
NCT05824507
Endometriosis and Chronic Endometritis
NA trial testing Endometrial aspiration biopsies for CE diagnosis in Endometriosis in 64 participants. Completed in 30 September 2024.
30 June 2022
Quick facts
| Lead sponsor | Jagiellonian University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 64 |
| Start date | 1 June 2021 |
| Primary completion | 30 June 2022 |
| Estimated completion | 30 September 2024 |
| Sites | 1 location across Poland |
Drugs / interventions tested
- Endometrial aspiration biopsies for CE diagnosis
Conditions studied
- Endometriosis — all drugs for Endometriosis →
- Pelvic Pain — all drugs for Pelvic Pain →
- Infertility — all drugs for Infertility →
Sponsor
Jagiellonian University
Who can join
Adults 18 to 45, female only, with Endometriosis or Pelvic Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pelvic endometriosis is a complex estrogen-dependent inflammatory syndrome of unknown etiology, altering the microenvironment of the peritoneal cavity and probably endometrial receptivity, and adversely affecting the physiological processes associated with fertilization. Literature data suggest that the distribution of immune system cells in the eutopic endometrium in the presence of endometriosis differs from the physiological state. The functioning of the immune system seems to be significantly modified not only in the foci of endometriosis, but also in the eutopic endometrium, affecting its physiological functions. Chronic endometritis (CE) is a potential factor impairing endometrial receptivity in the course of endometriosis. However, it is not known whether CE is one of the complications of endometriosis or perhaps an element of its pathogenesis. At the moment, endometrial diagnostics is not obligatory in the treatment of endometriosis in women of reproductive age, but it could potentially bring additional benefits and contribute to the improvement of obstetric results and increase the effectiveness of infertility treatment in women with endometriosis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Pelvic peritoneal endometriosis is linked to the endometrial inflammatory profile: a prospective cohort study.
Gawron I, Derbisz K, Jach R, Trojnarska D, et al · · 2025 · cited 3× · PMID 40033263 · DOI 10.1186/s12905-025-03632-3
Verify or expand the search:
- PubMed search for NCT05824507
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Jagiellonian University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05824507 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jagiellonian University
- Last refreshed: 12 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05824507.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing