NCT05824052 is a NA clinical trial of Ozone injection in Knee Osteoarthritis, sponsored by Uskudar State Hospital.

Who is sponsoring NCT05824052?

NCT05824052 is sponsored by Uskudar State Hospital.

What drugs are being tested in NCT05824052?

Interventions in NCT05824052: Ozone injection.

What condition does NCT05824052 study?

NCT05824052 studies Knee Osteoarthritis.

Is NCT05824052 still recruiting?

NCT05824052 is currently completed. Last updated 25 May 2023.

Last reviewed 2023-05-25 · How we verify

NCT05824052

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Investigating the Impact of Ex Vivo Ozone Injection on Synovial Fluids in Patients Diagnosed With Knee Osteoarthritis

Completed NA Last updated 25 May 2023

What this trial tests

NA trial testing Ozone injection in Knee Osteoarthritis in 82 participants. Completed in 24 May 2023.

Timeline

21 April 2023

Primary endpoint
20 May 2023

24 May 2023

Quick facts

Lead sponsor	Uskudar State Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	82
Start date	21 April 2023
Primary completion	20 May 2023
Estimated completion	24 May 2023
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Ozone injection — full drug profile →

Conditions studied

Knee Osteoarthritis — all drugs for Knee Osteoarthritis →

Sponsor

Uskudar State Hospital

Who can join

Adults 18 to 90, any sex, with Knee Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this study is to examine the effect of varying ozone doses on the levels of pro-inflammatory cytokines in synovial fluid collected from individuals with knee osteoarthritis.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Ozone therapy for knee osteoarthritis: a literature visualization analysis of research hotspots and prospects.
Liu Q, Liu J, Cao G, Liu Y, et al · · 2025 · cited 5× · PMID 39648327 · DOI 10.4103/mgr.medgasres-d-24-00099
The impact of ex vivo ozone injection into the synovial fluid in patients with knee osteoarthritis: A controlled clinical trial.
Ata E, Özgüç S, Temel MH, Beyaztaş H, et al · · 2024 · cited 1× · PMID 39507835 · DOI 10.46497/archrheumatol.2024.10375

Verify or expand the search:

Other recruiting trials for Knee Osteoarthritis

Currently open trials in the same condition.

NCT06906939 — A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression · EARLY_PHASE1 · recruiting
NCT05823727 — Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing Afte · NA · recruiting
NCT07370480 — Knee Osteoarthritis and Thermal Spa Treatment · NA · recruiting
NCT07507175 — Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis · NA · recruiting
NCT07386600 — Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA · NA · recruiting

Other Uskudar State Hospital trials

Trials by the same sponsor.

NCT05760105 — Awareness of Osteoporosis in Ankylosing Spondylosis Patients · unknown
NCT05882838 — The Level of Knowledge and Awareness of Myofascial Pain Syndrome in the Turkish Population · unknown
NCT05760651 — Awareness of Osteoporosis in Multiple Sclerosis Patients · completed
NCT05883215 — Effects of Social Media Usage on Pain Catastrophizing and Disease Impact in Female Patients With Fibromyalgia Syndrome · unknown
NCT05738785 — Risk of Osteoporotic Fracture in Home Care Patients in Turkey · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05824052 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Uskudar State Hospital
Last refreshed: 25 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05824052.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing