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NCT05823363
Vaginal Cuff Infiltration With Liposomal Bupivacaine for Pain Relief: A Double Blind, Randomized Controlled Trial
Phase 4 trial testing Exparel with Bubivacaine in Postoperative Pain. Withdrawn.
9 September 2024
Quick facts
| Lead sponsor | Olivia Sher |
|---|---|
| Phase | Phase 4 |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Start date | 9 September 2024 |
| Primary completion | 9 September 2024 |
| Estimated completion | 9 September 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Exparel with Bubivacaine — full drug profile →
- Bupivacaine only
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
Sponsor
Olivia Sher
Who can join
18 and older, female only, with Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal is to find out if Exparel (liposomal bupivacaine) given as an injection decreases pain score if given into the vaginal cuff right before starting the minimally invasive (robotic-assisted or laparoscopic) total hysterectomy in patients scheduled for benign indication? Participants will write down 1. pain score at various intervals 2. pain medication used Treatment patients will receive 1)intervention arm will receive Exparel mixed with bupivicaine 2)control arm will receive bupivicaine only
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05823363
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Other Olivia Sher trials
Trials by the same sponsor.
- NCT06498908 — Intracervical Balloon Placement With Nitrous Oxide Administration · Phase 3 · withdrawn
- NCT07508709 — Personalized Nutrition During Pregnancy · NA · withdrawn
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05823363 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Olivia Sher
- Last refreshed: 3 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05823363.
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