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NCT05818813: RDN flow
The Long-term Safety and Effect of Renal Denervation
trial testing Renal denervation in Hypertension in 9 participants. Terminated before completion.
16 April 2024
Quick facts
| Lead sponsor | Imperial College Healthcare NHS Trust |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 9 |
| Start date | 27 April 2021 |
| Primary completion | 16 April 2024 |
| Estimated completion | 16 April 2024 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Renal denervation
Conditions studied
- Hypertension — all drugs for Hypertension →
Sponsor
Imperial College Healthcare NHS Trust
Who can join
18 and older, any sex, with Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to learn about the effects of renal denervation in patients with resistant hypertension. The main question it aims to answer is: What are the long term effects of renal denervation on blood pressure and flow within the arteries? Participants will undergo an assessment of their blood pressure, echocardiogram and invasive measurements of blood pressure and flow in the aorta and renal arteries before undergoing the renal denervation procedure. 6 months later these assessments will be repeated.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05818813
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Renal denervation
Trials testing the same drug.
- NCT04535050 — DENEX Renal Denervation in Patients With Hypertension on no Antihypertensive Medications · NA · unknown
- NCT04264403 — Renal Denervation in Chronic Kidney Disease - RDN-CKD Study · NA · unknown
- NCT04314557 — Renal Arterial Denervation in Sympathetic Dysautonomia · completed
- NCT04248530 — DENEX Renal Denervation in Patients With Uncontrolled Hypertension: Safety Study · NA · completed
Other recruiting trials for Hypertension
Currently open trials in the same condition.
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- NCT07238556 — A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors · NA · recruiting
- NCT07238400 — Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia · Phase 2 · recruiting
- NCT07135505 — Early Time-Restricted Eating in Older Adults With Hypertension · NA · recruiting
Other Imperial College Healthcare NHS Trust trials
Trials by the same sponsor.
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- NCT04904484 — A Safety Assessment of the iZephyr Hood for NIV in COVID-19 Patients · NA · unknown
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05818813 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Imperial College Healthcare NHS Trust
- Last refreshed: 27 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05818813.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing