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NCT05818618
Impact of Topical Clobetasol on Gingival Crevicular Fluid miRNAs in Subjects Affected by Oral Lichen Planus
NA trial testing Clobetasol Topical Gel in Oral Lichen Planus in 64 participants. Completed in 10 August 2023.
5 July 2023
Quick facts
| Lead sponsor | University of Catania |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 64 |
| Start date | 12 March 2020 |
| Primary completion | 5 July 2023 |
| Estimated completion | 10 August 2023 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Clobetasol Topical Gel
- Placebo
Conditions studied
- Oral Lichen Planus — all drugs for Oral Lichen Planus →
Sponsor
University of Catania
Who can join
Adults 18 to 75, any sex, with Oral Lichen Planus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
According to recent research, microRNAs (miRNAs) may function as early disease indicators and contribute to the severity of a number of precancerous and malignant oral disorders. The aim of the present study, through a double-blind randomized controlled trial design, is to analyze in the gingival crevicular fluid (GCF) as a non-invasive approach the impact of topical clobetasol on miRNAs expression in subjects affected by oral lichen planus (OLP).
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05818618
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Oral Lichen Planus
Currently open trials in the same condition.
- NCT06981767 — Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus · Phase 2 · recruiting
- NCT07131813 — Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus · Phase 4 · recruiting
- NCT06932848 — The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus · NA · recruiting
- NCT07100613 — Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus · Phase 2 · recruiting
- NCT06233591 — Evaluating LP-10 in Subjects With OLP · Phase 2 · active not recruiting
Other University of Catania trials
Trials by the same sponsor.
- NCT07455643 — Closed-loop Response to Unannounced Mixed and Carbohydrates-rich Breakfasts · NA · completed
- NCT06831487 — Analysis of Line-Field Confocal Optical Coherence Tomography (LC-OCT) in Characterization of Gingival Systemic Health, G · NA · enrolling by invitation
- NCT06725095 — Effects of Enamel Matrix Derivative in the Treatment of Peri-implant Mucositis · NA · enrolling by invitation
- NCT06020937 — Olfactory and Trigeminal Functions in Patients With Multiple Sclerosis: Case-control Study · not yet recruiting
- NCT07300657 — Impact of an AI-Based Chatbot on Implant Patient Management: RCT · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05818618 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Catania
- Last refreshed: 25 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05818618.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing