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NCT05816473
Artificial Intelligent Clinical Decision Support System Simulation Center Study for Technology Acceptance
NA trial testing LLM in Gastrointestinal Hemorrhage in 106 participants. Completed in 31 December 2024.
31 December 2024
Quick facts
| Lead sponsor | Yale University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | parallel |
| Masking | none |
| Primary purpose | health services research |
| Enrollment | 106 |
| Start date | 23 May 2023 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- LLM
Conditions studied
- Gastrointestinal Hemorrhage — all drugs for Gastrointestinal Hemorrhage →
Sponsor
Yale University
Who can join
Eligibility, any sex, with Gastrointestinal Hemorrhage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this research study is to measure the effect on of a large language model interface on the usability, attitudes, and provider trust when using a machine learning algorithm-based clinical decision support system in the setting of bleeding from the upper gastrointestinal tract (upper GIB). Specifically, the investigators are looking to assess the optimal implementation of such machine learning algorithms in simulation scenarios to best engender trust and improve usability. Participants will be randomized to either machine learning algorithm alone or algorithm with a large language model interface and exposed to simulation cases of upper GIB.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Usability and adoption in a randomized trial of GutGPT a GenAI tool for gastrointestinal bleeding.
Chung S, Giuffrè M, Rajashekar N, Pu Y, et al · · 2025 · cited 2× · PMID 40825997 · DOI 10.1038/s41746-025-01896-5
Verify or expand the search:
- PubMed search for NCT05816473
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of LLM
Trials testing the same drug.
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Other recruiting trials for Gastrointestinal Hemorrhage
Currently open trials in the same condition.
- NCT07002359 — Assessment of Laboratory Parameters and Imaging Findings in Patients With Gastrointestinal Bleeding · active not recruiting
Other Yale University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05816473 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yale University
- Last refreshed: 10 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05816473.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing