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NCT05811208
Use of Pupillometry for Pain Assessment in ICU Patients with Delirium
trial testing automated pupillometry in Delirium in 50 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | St. Anne's University Hospital Brno, Czech Republic |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 May 2023 |
| Primary completion | 31 December 2025 |
| Estimated completion | 1 January 2026 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- automated pupillometry
- questionnaire
Conditions studied
- Delirium — all drugs for Delirium →
- Pain, Postoperative — all drugs for Pain, Postoperative →
Sponsor
St. Anne's University Hospital Brno, Czech Republic
Who can join
18 and older, any sex, with Delirium or Pain, Postoperative. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pain assessment in intensive care patients is a constant challenge. Approximately 50% to 80% of patients report pain at rest or during medical or nursing interventions (for example endotracheal suctioning, mobilization and rehabilitation, presence and care of invasive inputs, etc.). Obstacles to pain assessment and management are most often due to interference with communication due to impaired consciousness, airway support and connection to artificial pulmonary ventilation, or the effect of administered medication. Patients in intensive care are prone to delirium. Delirium can compromise patients' ability to verbalise pain for a variety of reasons (e.g. due to impaired attention, memory, thinking and language barriers). Also, pain and inadequate analgesia are risk factors for delirium. Pupillary reflex changes and their identification by automated pupillometry have yielded positive results regarding nociception assessment in adult and pediatric patients and in perioperative and postoperative care. At the same time, the response of these patients to opioid administration was investigated. The aim was to improve their analgesia. The aim of this study is to find out whether, there is an association between automated pupillometry and selected objective pain measurement scales in The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) positive patients after surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05811208
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
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Currently open trials in the same condition.
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- NCT07488468 — Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures · recruiting
- NCT07136207 — Development and Validation of Delirium Recognition Using Computer Vision in Neuro-critical Patients · recruiting
Other St. Anne's University Hospital Brno, Czech Republic trials
Trials by the same sponsor.
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- NCT06989229 — The Effect of Perioperative Nutritional Care on Recovery After Knee and Hip Replacement Surgery · recruiting
- NCT06579274 — Evaluation of the Safety and Efficacy of Parecoxib in Patients With Subarachnoid Hemorrhage · Phase 2 · not yet recruiting
- NCT06702059 — Cardiopulmonary Exercise Testing in Cardiosurgery Patients · recruiting
- NCT05861089 — Rest PETCO2 As a Predictor of Post-operative Complications · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05811208 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. Anne's University Hospital Brno, Czech Republic
- Last refreshed: 20 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05811208.
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