Last reviewed · How we verify
NCT05807854
RSA Vs RCR for Massive RCTs
NA trial testing Arthroscopy in Rotator Cuff Tears in 160 participants. Currently enrolling.
1 March 2027
Quick facts
| Lead sponsor | La Tour Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 160 |
| Start date | 1 March 2023 |
| Primary completion | 1 March 2027 |
| Estimated completion | 1 March 2027 |
| Sites | 2 locations across Switzerland, United States |
Drugs / interventions tested
- Arthroscopy
- Reverse Shoulder Arthroplasty
Conditions studied
- Rotator Cuff Tears — all drugs for Rotator Cuff Tears →
Sponsor
La Tour Hospital
Who can join
Adults 60 to 80, any sex, with Rotator Cuff Tears. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Different treatment options are available for massive or irreparable rotator cuff tears. An arthroscopic or an open repair approach is possible in the majority of cases and functional outcomes are improved, particularly when a complete arthroscopic repair can be achieved. However, the healing rate of massive rotator cuff tears after repair may remain low and failure of healing is associated with progression of arthritis. An alternative to arthroscopic or open repair is reverse shoulder arthroplasty which decreases pain and improves function, active shoulder elevation and quality of life. The primary goal of this prospective multicentric randomized study is to determine if there is a difference of functional outcomes between rotator cuff repair (RCR) repair and reverse shoulder arthroplasty (RSA).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Treatment of degenerative massive rotator cuff tears: a study protocol for a randomized non-inferiority comparative surgical trial.
Lädermann A, Pernoud A, Cochard B, Bothorel H. · · 2025 · PMID 40759980 · DOI 10.1186/s13063-025-08990-9
Verify or expand the search:
- PubMed search for NCT05807854
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Arthroscopy
Trials testing the same drug.
- NCT06747767 — Early Outcomes of Arthroscopic Versus Open Reduction for Developmental Dysplasia of the Hip in Children · NA · completed
- NCT04758585 — Non-adherence to Pain Medication Increases Risk of Postoperative Frozen Shoulder · NA · completed
- NCT03100799 — An Exploratory Clinical Study to Investigate Biomarkers of Senescence in Patients With Osteoarthritis of the Knee · NA · completed
Other recruiting trials for Rotator Cuff Tears
Currently open trials in the same condition.
- NCT07383038 — Effect of Mobilization With Movement in Patients With Rotator Cuff Lesions · NA · recruiting
- NCT06918041 — FiberLocker® System Augmentation of Rotator Cuff Repairs · NA · recruiting
- NCT06886932 — Pain Education After Rotator Cuff Surgery · recruiting
- NCT07001566 — The Impact of Cervical Radiculopathy on Functionality in Patients Undergoing Rotator Cuff Repair · recruiting
- NCT06733480 — Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue · NA · recruiting
Other La Tour Hospital trials
Trials by the same sponsor.
- NCT07283627 — Exploring the Evolution of Quality of Life and Emotional Distress Among Cancer Patients Participating in Mind-body Thera · enrolling by invitation
- NCT06963983 — Virtual Reality Rehabilitation for Shoulder Pathologies · NA · recruiting
- NCT06145815 — Machine Learning Predictive Model for Rotator Cuff Repair Failure · completed
- NCT06157788 — Cerebral Activation and Apprehension in Patients With Shoulder Instability. · completed
- NCT05660031 — Treatment of the Biceps With Concomitant Supraspinatus Tears · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05807854 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by La Tour Hospital
- Last refreshed: 26 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05807854.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing