Who is sponsoring NCT05807711?

NCT05807711 is sponsored by Alexandria University.

What drugs are being tested in NCT05807711?

Interventions in NCT05807711: L-Methyl Folate and methylcobalamine.

What condition does NCT05807711 study?

NCT05807711 studies End Stage Renal Disease, Hypertension, Renal.

Is NCT05807711 still recruiting?

NCT05807711 is currently completed. Last updated 13 January 2025.

Last reviewed 2025-01-13 · How we verify

NCT05807711

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of L-methylfolate and Methylcobalamine in Treating Resistant Hypertension Associated With Elevated Serum Homocysteine in Hemodialysis Patients.

Completed Phase 4 Last updated 13 January 2025

What this trial tests

Phase 4 trial testing L-Methyl Folate and methylcobalamine in End Stage Renal Disease in 51 participants. Completed in 1 May 2024.

Timeline

1 April 2023

Primary endpoint
1 May 2024

1 May 2024

Quick facts

Lead sponsor	Alexandria University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	51
Start date	1 April 2023
Primary completion	1 May 2024
Estimated completion	1 May 2024
Sites	1 location across Egypt

Drugs / interventions tested

L-Methyl Folate and methylcobalamine — full drug profile →

Conditions studied

End Stage Renal Disease — all drugs for End Stage Renal Disease →
Hypertension, Renal — all drugs for Hypertension, Renal →

Sponsor

Alexandria University

Who can join

Adults 18 to 75, any sex, with End Stage Renal Disease or Hypertension, Renal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to evaluate the efficacy of L-methylfolate in combination with methylcobalamine in reducing homocysteine blood levels in hypertensive end-stage renal disease patients on regular hemodialysis and its association with blood pressure control in treatment of resistant hypertension

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Efficacy of L-methylfolate and methylcobalamin in treating resistant hypertension associated with elevated serum homocysteine in hemodialysis patients.
Salem MS, Hamdy NA, Elghoneimy HA, El Gowelli HM. · · 2026 · PMID 41580678 · DOI 10.1186/s12882-025-04726-8

Verify or expand the search:

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Currently open trials in the same condition.

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Other Alexandria University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05807711 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Alexandria University
Last refreshed: 13 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05807711.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing