Adults 18 to 25, any sex, with Depression in Adolescence. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
BDI-II -PretestPrimary· BDI-II score at pre-test (1week before intervention)
The Beck Depression Inventory II (BDI-II) is a 21-item self-report questionnaire designed to measure the level of severity of disorders of depression. Items are scored from 0 to 3; higher scores indicate greater symptom severity. In the BDI-II values below 13 points are regarded as no or minimal depressive symptoms. Values between 14 and 19 points indicate a mild expression of depressive symptoms, values between 20 and 28 points a moderate severity. Scores between 29 and 63 are regarded as evidence of severe depressive disorder.
Group
Value
95% CI
online mindfulness-based cognitive therapy program
12.54
± 10.31
mental health education
14.42
± 11.5
BDI-II -PosttestPrimary· 1 week after the intervention, corresponding to Week 9
The Beck Depression Inventory II (BDI-II) is a 21-item self-report questionnaire designed to measure the level of severity of disorders of depression. Items are scored from 0 to 3; higher scores indicate greater symptom severity. In the BDI-II values below 13 points are regarded as no or minimal depressive symptoms. Values between 14 and 19 points indicate a mild expression of depressive symptoms, values between 20 and 28 points a moderate severity. Scores between 29 and 63 are regarded as evidence of severe depressive disorder.
Group
Value
95% CI
online mindfulness-based cognitive therapy program
7
± 7.83
mental health education
9.87
± 10.1
WHOQOL-BREF-TW -PretestPrimary· WHOQOL-BREF-TW score at pre-test (1week before intervention)
The World Health Organization Quality-of-Life Scale (WHOQOL-BREF) is a 28-item self-report questionnaire with a five point rating scale for each item (from 1 to 5). There are four domains in WHOQOL-BREF, including physical health, psychological health, social relationships, and environment. The Physical Health domain consists of 7 items, with a total score range of 7 to 35; the Psychological domain includes 6 items, ranging from 6 to 30; the Social Relationships domain comprises 4 items, with scores ranging from 4 to 20; and the Environment domain contains 9 items, with a range of 9 to 45.
Tw
Overall quality of Life
Group
Value
95% CI
online mindfulness-based cognitive therapy program
3.38
± 0.75
mental health education
3.15
± 0.73
General Health facet
Group
Value
95% CI
online mindfulness-based cognitive therapy program
2.88
± 0.59
mental health education
2.65
± 0.75
Physical Health
Group
Value
95% CI
online mindfulness-based cognitive therapy program
26.31
± 3.96
mental health education
23.85
± 4.4
Psychological
Group
Value
95% CI
online mindfulness-based cognitive therapy program
18.38
± 4.73
mental health education
17.81
± 4.11
Social relationships
Group
Value
95% CI
online mindfulness-based cognitive therapy program
14.54
± 2.79
mental health education
13.96
± 1.95
Environment
Group
Value
95% CI
online mindfulness-based cognitive therapy program
33.81
± 4.54
mental health education
32
± 4.72
WHOQOL-BREF-TW -PosttestPrimary· 1 week after the intervention, corresponding to Week 9
The World Health Organization Quality-of-Life Scale (WHOQOL-BREF) is a 28-item self-report questionnaire with a five point rating scale for each item (from 1 to 5). There are four domains in WHOQOL-BREF, including physical health, psychological health, social relationships, and environment. The Physical Health domain consists of 7 items, with a total score range of 7 to 35; the Psychological domain includes 6 items, ranging from 6 to 30; the Social Relationships domain comprises 4 items, with scores ranging from 4 to 20; and the Environment domain contains 9 items, with a range of 9 to 45.
Tw
Overall quality of Life
Group
Value
95% CI
online mindfulness-based cognitive therapy program
3.87
± 0.69
mental health education
3.48
± 0.73
General Health facet
Group
Value
95% CI
online mindfulness-based cognitive therapy program
3.04
± 1.02
mental health education
3.13
± 0.92
Physical Health
Group
Value
95% CI
online mindfulness-based cognitive therapy program
28.13
± 4.32
mental health education
25.74
± 3.6
Psychological
Group
Value
95% CI
online mindfulness-based cognitive therapy program
21.13
± 5.15
mental health education
18.7
± 3.76
Social relationships
Group
Value
95% CI
online mindfulness-based cognitive therapy program
15.52
± 2.5
mental health education
14.7
± 2.18
Environment
Group
Value
95% CI
online mindfulness-based cognitive therapy program
36.39
± 5.32
mental health education
32.61
± 4.52
BAI -PretestSecondary· BAI score at pre-test (1week before intervention)
The Beck Anxiety Inventory (BAI) is a 21-item self-report measure designed to reflect the severity of somatic and cognitive symptoms of anxiety over the previous week. Items are scored from 0 to 3; higher scores indicate greater symptom severity. The BAI scores are classified as minimal anxiety (0 to 7), mild anxiety (8 to 15), moderate anxiety (16 to 25), and severe anxiety (30 to 63).
Group
Value
95% CI
online mindfulness-based cognitive therapy program
9.31
± 7.36
mental health education
8.65
± 7.65
BAI -PosttestSecondary· 1 week after the intervention, corresponding to Week 9
The Beck Anxiety Inventory (BAI) is a 21-item self-report measure designed to reflect the severity of somatic and cognitive symptoms of anxiety over the previous week. Items are scored from 0 to 3; higher scores indicate greater symptom severity. The BAI scores are classified as minimal anxiety (0 to 7), mild anxiety (8 to 15), moderate anxiety (16 to 25), and severe anxiety (30 to 63).
Group
Value
95% CI
online mindfulness-based cognitive therapy program
5.52
± 7.38
mental health education
6.52
± 6.71
OSA -PretestSecondary· OSA score at pre-test (1week before intervention)
The Occupational Self-Assessment (OSA) evaluates self-perceived occupational competence and environmental support. The questionnaire includes two sections: Self-Competence and Environment. The Self-Competence section has 21 items divided into three subscales-Skills/Performance (11 items), Habituation (5 items), and Volition (5 items)-and the Environment section has 8 items assessing perceived environmental support. Each item is rated on a 4-point scale, where 1 indicates the lowest and 4 the highest level of perceived competence or support. The possible score ranges are 11-44 for Skills/Perfor
Skills/Performance
Group
Value
95% CI
online mindfulness-based cognitive therapy program
33.62
± 4.73
mental health education
30.73
± 4.62
Habituation
Group
Value
95% CI
online mindfulness-based cognitive therapy program
14.42
± 2.76
mental health education
12.96
± 2.81
Volition
Group
Value
95% CI
online mindfulness-based cognitive therapy program
13.88
± 2.63
mental health education
12.69
± 2.9
Environment
Group
Value
95% CI
online mindfulness-based cognitive therapy program
27.42
± 3.7
mental health education
26.65
± 3.82
OSA -PosttestSecondary· 1 week after the intervention, corresponding to Week 9
The Occupational Self-Assessment (OSA) evaluates self-perceived occupational competence and environmental support. The questionnaire includes two sections: Self-Competence and Environment. The Self-Competence section has 21 items divided into three subscales-Skills/Performance (11 items), Habituation (5 items), and Volition (5 items)-and the Environment section has 8 items assessing perceived environmental support. Each item is rated on a 4-point scale, where 1 indicates the lowest and 4 the highest level of perceived competence or support. The possible score ranges are 11-44 for Skills/Perfor
Skills/Performance
Group
Value
95% CI
online mindfulness-based cognitive therapy program
35.3
± 4.99
mental health education
32.65
± 4.46
Habituation
Group
Value
95% CI
online mindfulness-based cognitive therapy program
16.35
± 2.74
mental health education
13.83
± 2.37
Volition
Group
Value
95% CI
online mindfulness-based cognitive therapy program
15.96
± 2.85
mental health education
14.04
± 3.31
Environment
Group
Value
95% CI
online mindfulness-based cognitive therapy program
28.7
± 3.78
mental health education
26.96
± 4.37
COPM -PretestSecondary· COPM score at pre-test (1week before intervention)
The Canadian Occupational Performance Measure (COPM) is an individualized measure designed for use by occupational therapists to detect self-perceived change in occupational performance problems over time. The therapist calculates an average COPM performance score and satisfaction score. These typically range between 1 and 10, where 1 indicates poor performance and low satisfaction, respectively, while 10 indicates very good performance and high satisfaction.
Performance
Group
Value
95% CI
online mindfulness-based cognitive therapy program
5.93
± 1.51
mental health education
4.62
± 1.46
Satisfaction
Group
Value
95% CI
online mindfulness-based cognitive therapy program
5.39
± 1.84
mental health education
4.22
± 1.77
COPM -PosttestSecondary· 1 week after the intervention, corresponding to Week 9
The Canadian Occupational Performance Measure (COPM) is an individualized measure designed for use by occupational therapists to detect self-perceived change in occupational performance problems over time. The therapist calculates an average COPM performance score and satisfaction score. These typically range between 1 and 10, where 1 indicates poor performance and low satisfaction, respectively, while 10 indicates very good performance and high satisfaction.
Performance
Group
Value
95% CI
online mindfulness-based cognitive therapy program
7.03
± 1.65
mental health education
6.01
± 1.37
Satisfaction
Group
Value
95% CI
online mindfulness-based cognitive therapy program
6.85
± 1.85
mental health education
6.06
± 1.66
Sponsor's own description
The goal of this interventional study is to examine the efficacy of the online mindfulness-based cognitive therapy program(MBCT) in youth (18-25 years old) with depressive symptoms. The main questions it aims to answer are:
* Whether the program could reduce depressive symptoms in university students.
* Whether the program could increase quality of life in university students.
* The effectiveness, acceptance, and practicability of the program for university students.
Participants in the experimental group would be arranged to attend online mindfulness-based cognitive programs for eight weeks. The control group would be educated the knowledge of mental health to manage their negative emotions.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
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Sponsor: as reported to ClinicalTrials.gov by Chung Shan Medical University
Last refreshed: 10 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05804877.