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NCT05804630
Efficacy and Safety of Articaine and Lidocaine in Extraction of Wisdom Teeth of Upper and Lower Jaws
NA trial testing Different dental anesthetic agents during wisdom tooth surgery (Orabloc®, Octocaine®, and Xylestesin-A®) in Wisdom Tooth in 60 participants. Status unknown.
31 January 2024
Quick facts
| Lead sponsor | National Taiwan University Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 15 March 2023 |
| Primary completion | 31 January 2024 |
| Estimated completion | 31 July 2024 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- Different dental anesthetic agents during wisdom tooth surgery (Orabloc®, Octocaine®, and Xylestesin-A®)
Conditions studied
- Wisdom Tooth — all drugs for Wisdom Tooth →
- Dental Impaction — all drugs for Dental Impaction →
Sponsor
National Taiwan University Hospital
Who can join
Adults 20 to 60, any sex, with Wisdom Tooth or Dental Impaction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Local anesthesia drugs and anesthesia technique play an imperative role in dental treatment. The purpose of this study was to compare the efficacy and safety of different dental local anesthetics drugs and brands in clinical use for the extraction of wisdom teeth.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Efficacy and safety of infiltration anesthesia with 4 % Articaine and block anesthesia with 2 % Lidocaine in the mandibular third molar extraction.
Huang NC, Chang HH, Lin CP. · · 2025 · PMID 40224063 · DOI 10.1016/j.jds.2025.01.018
Verify or expand the search:
- PubMed search for NCT05804630
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05804630 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
- Last refreshed: 7 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05804630.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing