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NCT05802433
The Genetic Effects on Vitamin D Supplementation
NA trial testing Vitamin D3 supplement in Vitamin D Deficiency in 67 participants. Status unknown.
25 August 2023
Quick facts
| Lead sponsor | St. Mary's University, Twickenham |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 67 |
| Start date | 16 May 2022 |
| Primary completion | 25 August 2023 |
| Estimated completion | 5 October 2023 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Vitamin D3 supplement
Conditions studied
- Vitamin D Deficiency — all drugs for Vitamin D Deficiency →
Sponsor
St. Mary's University, Twickenham
Who can join
Adults 18 to 65, any sex, with Vitamin D Deficiency. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Vitamin D is essential for skeletal growth and bone health, deficiency causes rickets and osteomalacia. In the UK 29% of adults have vitamin D deficiency. It is recommended all adults take 10µg vitamin D supplement daily. Genetic variations could alter vitamin D status by affecting vitamin D metabolism. Systematic reviews found variations in VDR, GC and CYP2R1 genes are associated with vitamin D deficiency. This study aims to assess the effects between vitamin D supplementation and variations in VDR, GC and CYP2R1 genes on vitamin D status.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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Nuclear receptors in health and disease: signaling pathways, biological functions and pharmaceutical interventions.
Jin P, Duan X, Huang Z, Dong Y, et al · · 2025 · cited 21× · PMID 40717128 · DOI 10.1038/s41392-025-02270-3
Verify or expand the search:
- PubMed search for NCT05802433
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Vitamin D Deficiency
Currently open trials in the same condition.
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- NCT07006714 — Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA) · Phase 4 · active not recruiting
- NCT07200011 — Effect of Vitamin D on the Clinical and Radiographic of Unsplinted Mandibular Implant Overdentures · active not recruiting
Other St. Mary's University, Twickenham trials
Trials by the same sponsor.
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- NCT07207096 — Observational Case Series of Patients With Parkinson's Disease (PD) Attending a Complementary Medicine Neuro-degenerativ · recruiting
- NCT07129200 — The Effects of Caffeine on Exercise Physiology and Time-trial Performance in a Hot Environment · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05802433 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by St. Mary's University, Twickenham
- Last refreshed: 6 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05802433.
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