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NCT05801861
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
NA trial testing Active 10-Hz TMS to the parietal cortex in Spatial Navigation in 60 participants. Currently enrolling.
31 August 2026
Quick facts
| Lead sponsor | Rutgers, The State University of New Jersey |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 60 |
| Start date | 24 March 2023 |
| Primary completion | 31 August 2026 |
| Estimated completion | 31 August 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Active 10-Hz TMS to the parietal cortex
- Active single pulse TMS to the parietal cortex
- Sham 10-Hz TMS to the right parietal cortex
- Sham single-pulse rTMS the rigt parietal cortex
Conditions studied
- Spatial Navigation — all drugs for Spatial Navigation →
Sponsor
Rutgers, The State University of New Jersey
Who can join
Adults 18 to 55, any sex, with Spatial Navigation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is believed to index the sensitivity of the parahippocampal cortex to spatial context. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in virtual navigation tasks, and if so, whether it would affect the spatial encoding of rewards and subsequent choices during task performance.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05801861
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Spatial Navigation
Currently open trials in the same condition.
- NCT05944601 — Exploring to Remediate Behavioral Disturbances of Spatial Cognition · NA · active not recruiting
Other Rutgers, The State University of New Jersey trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05801861 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rutgers, The State University of New Jersey
- Last refreshed: 17 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05801861.
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