Last reviewed · How we verify
NCT05801380: MEMORI-AD
Monitoring Drug Efficacy in Patients with Alzheimer's Disease
trial testing AChE inhibitor monotherapy in Alzheimer Disease in 60 participants. Currently enrolling.
14 February 2026
Quick facts
| Lead sponsor | University of the Philippines |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 14 February 2022 |
| Primary completion | 14 February 2026 |
| Estimated completion | 14 February 2026 |
| Sites | 1 location across Philippines |
Drugs / interventions tested
- AChE inhibitor monotherapy — full drug profile →
- AChE inhibitor and NMDA receptor antagonist combination therapy — full drug profile →
Conditions studied
- Alzheimer Disease — all drugs for Alzheimer Disease →
Sponsor
University of the Philippines
Who can join
65 and older, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will explore the different factors associated with drug response to acetylcholinesterase (AChE) inhibitor (donepezil) and NMDA receptor antagonist (memantine) in patients with Alzheimer's Disease.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
<u>M</u>onitoring drug <u>E</u>fficacy through <u>M</u>ulti-<u>O</u>mics <u>R</u>esearch initiative in <u>A</u>lzheimer's <u>D</u>isease (MEMORI-AD): A protocol for a multisite exploratory prospective cohort study on the drug response-related clinical, genetic, microbial and meta
Climacosa FMM, Anlacan VMM, Gordovez FJA, Reyes JCB, et al · · 2024 · cited 4× · PMID 39608999 · DOI 10.1136/bmjopen-2023-078660 -
Challenges in community-based recruitment of Alzheimer's disease cases: Experience of the monitoring drug efficacy through multi-omics research initiative in Alzheimer's disease (MEMORI-AD) study.
Climacosa FMM, Ornos EDB, Diwa ERS, Guantia MGR, et al · · 2026 · PMID 41929959 · DOI 10.1177/25424823261431318
Verify or expand the search:
- PubMed search for NCT05801380
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of the Philippines trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05801380 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of the Philippines
- Last refreshed: 7 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05801380.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing