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NCT05798169
Impact of Acute Hospitalisation and Resistance Training on Muscle Architecture and Physical Performance in Older Adults
NA trial testing Resistance training in Sarcopenia in 274 participants. Completed in 20 December 2024.
20 December 2024
Quick facts
| Lead sponsor | Odense University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 274 |
| Start date | 5 January 2023 |
| Primary completion | 20 December 2024 |
| Estimated completion | 20 December 2024 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Resistance training
Conditions studied
- Sarcopenia — all drugs for Sarcopenia →
- Functional Decline — all drugs for Functional Decline →
- Muscle Architecture — all drugs for Muscle Architecture →
- Gait Speed — all drugs for Gait Speed →
Sponsor
Odense University Hospital
Who can join
65 and older, any sex, with Sarcopenia or Functional Decline. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sarcopenia characterised by loss of muscle mass, muscle strength and physical performance burdens many older adults since the condition is related to functional decline. Periods of inactivity such as during hospitalisation leads to further functional decline. It has been reported that the loss of muscle mass associated with sarcopenia not only entails a decrease in muscle mass but also changes in muscle architecture. Knowledge on changes in muscle architecture is essential since it is one of the most important determinants on muscle strength and thus physical performance. The main objective of this study is to investigate changes in muscle architecture and physical performance during acute hospitalisation and after discharge in older adults and subsequently the effectiveness of resistance training of the lower limb during acute hospitalisation. If successful, our study could have a great impact on the individual, as well as societal level, due to a better understanding of the factors related to sarcopenia and the prevention of functional decline as a result of hospitalisation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Emerging Links Between Ferroptosis and Neurodegeneration: Implications for Disease Mechanisms and Nutraceutical Interventions.
Ali A, Babar Q, Saeed A, Sergi D, et al · · 2025 · cited 2× · PMID 40475985 · DOI 10.1002/fsn3.70385
Verify or expand the search:
- PubMed search for NCT05798169
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Odense University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05798169 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Odense University Hospital
- Last refreshed: 27 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05798169.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing