A Multicenter Collaborative Clinical Study of Umbilical Cord Blood Combined With Umbilical Cord Derived Mesenchymal Stem Cells in the Treatment of Bone Marrow Failure Disorders

NCT05794425 Phase 1/Phase 2 UNKNOWN

The multicenter collaborative clinical study conducted a systematic clinical observation in the treatment of bone marrow failure diseases via UCB\&UC-MSCs , in order to observe its clinical efficacy and safety.

Details

Lead sponsor	Shandong Qilu Stem Cells Engineering Co., Ltd.
Phase	Phase 1/Phase 2
Status	UNKNOWN
Enrolment	100
Start date	2023-08-01
Completion	2026-04

Conditions

• Bone Marrow Failure Disorders

Interventions

• Cyclosporine A
• Umbilical cord blood & Umbilical cord derived mesenchymal stem cells

Primary outcomes

• Objective Response Rate (ORR) — Up to two years
  To evaluate efficacy of UCB in combination with UC-MSCs in the treatment of bone marrow failure disorders

Countries

China