Who is sponsoring TRAIT?

TRAIT is sponsored by Bryan Cotton.

What condition does TRAIT study?

TRAIT studies Trauma Injury, Thromboembolism, Venous Thromboembolism.

What drugs are being tested in TRAIT?

Interventions: Thrombate infusion, Placebo.

What is the status of TRAIT?

TRAIT is currently ENROLLING_BY_INVITATION.

Last reviewed 2025-05-09 · How we verify

Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism (TRAIT)

NCT05794165 Phase 2 ENROLLING_BY_INVITATION

The purpose of this study is to determine if additional interventions will assist with decreasing the risk and/or severity of thromboembolism (clotting complications) in patients who have experienced a major traumatic event.

Details

Lead sponsor	Bryan Cotton
Phase	Phase 2
Status	ENROLLING_BY_INVITATION
Enrolment	314
Start date	2023-09-27
Completion	2027-03

Conditions

Trauma Injury
Thromboembolism
Venous Thromboembolism

Interventions

Thrombate infusion
Placebo

Primary outcomes

Number of participants with incidences of venous thromboembolism (VTE ) — 14 days post hospital admission
Number of participants with incidence of antifactor Xa (anti-FXa) of ≥0.2 IU/mL — 14 days post hospital admission

Countries

United States