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NCT05793294: CHAMP

Child Health, Nutrition and Microbiome Development

Active, enrolled Last updated 5 January 2026
What this trial tests

trial in Malnutrition in 70 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
10 May 2024
Primary endpoint
30 May 2025
31 May 2026

Quick facts

Lead sponsorKhyber Medical University Peshawar
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment70
Start date10 May 2024
Primary completion30 May 2025
Estimated completion31 May 2026
Sites2 locations across Pakistan

Conditions studied

Sponsor

Khyber Medical University Peshawar

Who can join

Adults 1 Day to 28 Days, any sex, with Malnutrition or Stunting. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Childhood malnutrition is a global public health issue with devastating consequences on the health, well-being, and psychosocial development of children. Emerging evidence suggests that malnourished children have immature gut microbiota compared to age-matched healthy controls and it does not repair even after nutritional interventions. The present study aims to characterize how the gut microbiome develops during the first two years of life in children residing in malnutrition endemic areas of Khyber Pakhtunkhwa, the region with the highest prevalence of childhood malnutrition in Pakistan and the region.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan.
    Shahzad M, Ismail M, Misselwitz B, Saidal A, et al · · 2024 · cited 1× · PMID 40979405 · DOI 10.12688/f1000research.158415.2
  2. Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
    Shahzad M, Ismail M, Misselwitz B, Saidal A, et al · · 2025 · DOI 10.12688/f1000research.158415.2
  3. Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
    Shahzad M, Ismail M, Misselwitz B, Saidal A, et al · · 2024 · DOI 10.12688/f1000research.158415.1
  4. Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
    Shahzad M, Ismail M, Misselwitz B, Saidal A, et al · · 2024 · DOI 10.1101/2024.10.23.24315915

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Other recruiting trials for Malnutrition

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05793294.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing