Last reviewed · How we verify
NCT05793294: CHAMP
Child Health, Nutrition and Microbiome Development
trial in Malnutrition in 70 participants. Participants enrolled and being followed up; not accepting new ones.
30 May 2025
Quick facts
| Lead sponsor | Khyber Medical University Peshawar |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 70 |
| Start date | 10 May 2024 |
| Primary completion | 30 May 2025 |
| Estimated completion | 31 May 2026 |
| Sites | 2 locations across Pakistan |
Conditions studied
- Malnutrition — all drugs for Malnutrition →
- Stunting — all drugs for Stunting →
- Wasting — all drugs for Wasting →
- Underweight — all drugs for Underweight →
Sponsor
Khyber Medical University Peshawar
Who can join
Adults 1 Day to 28 Days, any sex, with Malnutrition or Stunting. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Childhood malnutrition is a global public health issue with devastating consequences on the health, well-being, and psychosocial development of children. Emerging evidence suggests that malnourished children have immature gut microbiota compared to age-matched healthy controls and it does not repair even after nutritional interventions. The present study aims to characterize how the gut microbiome develops during the first two years of life in children residing in malnutrition endemic areas of Khyber Pakhtunkhwa, the region with the highest prevalence of childhood malnutrition in Pakistan and the region.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan.
Shahzad M, Ismail M, Misselwitz B, Saidal A, et al · · 2024 · cited 1× · PMID 40979405 · DOI 10.12688/f1000research.158415.2 -
Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
Shahzad M, Ismail M, Misselwitz B, Saidal A, et al · · 2025 · DOI 10.12688/f1000research.158415.2 -
Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
Shahzad M, Ismail M, Misselwitz B, Saidal A, et al · · 2024 · DOI 10.12688/f1000research.158415.1 -
Child health, nutrition and gut microbiota development during the first two years of life; study protocol of a prospective cohort study from the Khyber Pakhtunkhwa, Pakistan
Shahzad M, Ismail M, Misselwitz B, Saidal A, et al · · 2024 · DOI 10.1101/2024.10.23.24315915
Verify or expand the search:
- PubMed search for NCT05793294
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05793294 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Khyber Medical University Peshawar
- Last refreshed: 5 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05793294.
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