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NCT05792371
The Role of Type H Vessel Formation in Induced Membrane of Patients With Critical Size Bone Defect
NA trial testing induced membrane technique in Bone Injury in 30 participants. Status unknown.
1 April 2023
Quick facts
| Lead sponsor | Chang Gung Memorial Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 30 |
| Start date | 1 April 2023 |
| Primary completion | 1 April 2023 |
| Estimated completion | 2 January 2026 |
Drugs / interventions tested
- induced membrane technique
- Bone graft (Stage II of IMT)
Conditions studied
- Bone Injury — all drugs for Bone Injury →
Sponsor
Chang Gung Memorial Hospital
Who can join
Adults 20 to 80, any sex, with Bone Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to test the role of type H vessel and investigate the mechanism of its regulation in induced membrane created by induced membrane technique in patients with open fracture, aged between 20 and 80. The main questions to answer are: * Whether type H vessel will be critical for induced membrane-mediated bone healing? * Whether type H vessel will be a biomarker for diagnosing bone healing in patients with open fracture? * To find out a circulating indicator for type H vessel in patients with open fracture undergoing induced membrane technique. Participants will be enrolled to collect tissues of induced membrane and blood samples to detect type H vessel and measure the biomarkers of type H vessel, investigating their correlation with the capacity of bone healing. To avoid selection bias of treatment, the grouping will be achieved by a randomized protocol qualified clinical trial center of Chang Gung Memorial Hospital to divide into with induced membrane and without induced membrane. Researchers will compare these two groups to test our hypothesis that type H vessel in important in induced membrane and their corresponding biomarkers.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05792371
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Related trials
Other recruiting trials for Bone Injury
Currently open trials in the same condition.
- NCT06249906 — Efficacy of Bioceramic Materials for Bone Defects Repair · NA · recruiting
Other Chang Gung Memorial Hospital trials
Trials by the same sponsor.
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- NCT07489833 — Metabolomic Pathways and Traditional Chinese Medicine Body Constitution in Cancer-related Fatigue · not yet recruiting
- NCT07496528 — The ACURE Trial: Acupuncture for Colorectal Recovery · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05792371 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chang Gung Memorial Hospital
- Last refreshed: 31 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05792371.
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