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NCT05789992: eMAC
Evaluation of Equivalent Minimum Alveolar Concentration (eMAC) During Propofol/Remifentanil Anesthesia
NA trial testing Propofol in General Anaesthesia in 62 participants. Completed in 29 April 2023.
29 April 2023
Quick facts
| Lead sponsor | Zhang Haopeng |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 62 |
| Start date | 3 April 2023 |
| Primary completion | 29 April 2023 |
| Estimated completion | 29 April 2023 |
| Sites | 1 location across China |
Drugs / interventions tested
- Propofol (Propofol) — full drug profile →
- Low Remifentanil — full drug profile →
- Heigh Remifentanil — full drug profile →
- Intubation
- tetanic electrical stimulation
Conditions studied
- General Anaesthesia — all drugs for General Anaesthesia →
Sponsor
Zhang Haopeng — full company profile →
Who can join
18 and older, any sex, with General Anaesthesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to verify the accuracy of eMAC compared to Bispectral Index (BIS) for depth and nociceptive stimulation monitoring of anesthesia during general anesthesia.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Feasibility Study of an Indicator of Equivalent Potency of Multiple Anesthetics Normalized by Minimum Alveolar Concentration Derived From Response Surface Models.
Zhang H, Zhang J, Li X, He S, et al · · 2026 · PMID 40244902 · DOI 10.1213/ane.0000000000007514
Verify or expand the search:
- PubMed search for NCT05789992
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for General Anaesthesia
Currently open trials in the same condition.
- NCT07037186 — Burst Suppressions in Diabetic Elderly · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05789992 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zhang Haopeng
- Last refreshed: 15 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05789992.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing