NCT05783492 is a Phase 3 clinical trial of Intranasal ketamine in Procedural Sedation, sponsored by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's.

What drugs are being tested in NCT05783492?

Interventions in NCT05783492: Intranasal ketamine.

What condition does NCT05783492 study?

NCT05783492 studies Procedural Sedation.

Is NCT05783492 still recruiting?

NCT05783492 is currently withdrawn. Last updated 24 March 2023.

Last reviewed 2023-03-24 · How we verify

NCT05783492

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

INK Feasibility Study

Withdrawn Phase 3 Last updated 24 March 2023

What this trial tests

Phase 3 trial testing Intranasal ketamine in Procedural Sedation. Withdrawn.

Timeline

1 January 2024

Primary endpoint
31 March 2024

30 April 2024

Quick facts

Lead sponsor	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Phase	Phase 3
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Start date	1 January 2024
Primary completion	31 March 2024
Estimated completion	30 April 2024

Drugs / interventions tested

Intranasal ketamine — full drug profile →

Conditions studied

Procedural Sedation — all drugs for Procedural Sedation →

Sponsor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Who can join

Adults 7 to 17, any sex, with Procedural Sedation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The trial (Intranasal ketamine for procedural sedation in children: a randomized controlled non-inferiority multicenter trial or INK; ReDA 5496; CTO 1545) is being scheduled for launch in Spring 2019. Due to the possibility of failure of the experimental intervention (intranasal ketamine 10 mg/kg), the data safety monitoring board (DSMB) and statistical methods team would like to explore the possibility of developing a stopping rule to prevent patients from being enrolled in a futile trial and conserve resources. In order to get accurate data to develop a statistically robust stopping rule, it is necessary to conduct a cohort study of patients that receive the INK trial's experimental intervention and according to it's protocol. This cohort study will help estimate the chance of adequate sedation and inform the final dosing protocol for the INK trial.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Intranasal ketamine

Trials testing the same drug.

NCT07180095 — Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evalua · Phase 1, PHASE2 · not yet recruiting
NCT07305883 — Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain · Phase 3 · not yet recruiting
NCT07055828 — Nebulized vs. IV Ketamine in Preventing Shivering Post Spinal Anesthesia · NA · active not recruiting
NCT04150757 — Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED · Phase 3 · terminated
NCT03539887 — Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse · Phase 3 · completed

Other recruiting trials for Procedural Sedation

Currently open trials in the same condition.

NCT07213544 — Remimazolam vs Propofol in Laser Burn Cases · Phase 4 · recruiting
NCT07336628 — Propofol vs Remifentanil for Sedation in Gastroscopy · NA · active not recruiting
NCT06414395 — The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients U · Phase 4 · recruiting

Other London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's trials

Trials by the same sponsor.

NCT07588711 — Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Neuropathic Pain Following Spinal Cord Injury · NA · not yet recruiting
NCT07585292 — Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Musculoskeletal Pain in Cerebral Palsy · NA · not yet recruiting
NCT07510906 — Evaluation of a Prostate-Targeted PET Imaging System (P-PET) for Detecting Prostate Cancer · NA · not yet recruiting
NCT03166072 — Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers · NA · not yet recruiting
NCT06035809 — Sensory Motor Arousal Regulation Treatment (SMART) Study · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05783492 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Last refreshed: 24 March 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05783492.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing