Last reviewed · How we verify
NCT05782738: T-REX
Reverse T-stenting and Minimal Protrusion With External Minicrush for Treatment of Complex Coronary Bifurcation
NA trial testing Percutaneous Coronary Intervention in Coronary Artery Disease in 361 participants. Not yet recruiting.
1 June 2026
Quick facts
| Lead sponsor | San Luigi Gonzaga Hospital |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 361 |
| Start date | 1 June 2023 |
| Primary completion | 1 June 2026 |
| Estimated completion | 1 June 2029 |
| Sites | 5 locations across Italy |
Drugs / interventions tested
- Percutaneous Coronary Intervention
Conditions studied
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
- Coronary Stenosis — all drugs for Coronary Stenosis →
- Coronary Disease — all drugs for Coronary Disease →
Sponsor
San Luigi Gonzaga Hospital
Who can join
18 and older, any sex, with Coronary Artery Disease or Coronary Stenosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Reverse T-stenting And Minimal Protrusion (Reverse TAP) is an up-front 2-stent technique that treats complex coronary bifurcation. Compared to crush techniques, it does not require crushing of the side branch stent but only minimal protrusion of the side branch stent before main vessel stenting. Nowadays, no studies compare the Reverse-TAP and the External Minicrush in treating complex coronary bifurcation, so eventually, procedural, clinical and safety differences remain unknown.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05782738
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Percutaneous Coronary Intervention
Trials testing the same drug.
- NCT07373678 — CABG Versus PCI in Patients With Isolated LAD Chronic Total Occlusion · completed
- NCT07303439 — Randomised Trial of Dual Device Treatment Involving Drug-coated Balloon Angioplasty and Drug-eluting Stent Implantation · NA · recruiting
- NCT07034157 — A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Cor · recruiting
- NCT06654453 — The Thrombus Aspiration During PCI After Thrombolysis in STEMI · NA · recruiting
- NCT06779110 — Intracoronary Optical Coherence Tomography Guidance Vs. Angiography Only Guidance for Treatment of Coronary In-stent Res · NA · recruiting
Other recruiting trials for Coronary Artery Disease
Currently open trials in the same condition.
- NCT07399002 — LONG NAGOMI™ PMCF STUDY · recruiting
- NCT07420582 — Antegrade Autologous Blood Reinfusion After CPB · recruiting
- NCT07493603 — A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease · Phase 1, PHASE2 · recruiting
- NCT06535568 — Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO · NA · recruiting
- NCT07286578 — A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Under · NA · recruiting
Other San Luigi Gonzaga Hospital trials
Trials by the same sponsor.
- NCT07442526 — AGECTO Study: PCI vs. Optimal Medical Therapy for CTO in the Octogenarian Patients · active not recruiting
- NCT06779110 — Intracoronary Optical Coherence Tomography Guidance Vs. Angiography Only Guidance for Treatment of Coronary In-stent Res · NA · recruiting
- NCT06484647 — Comparing T-stenting And Minimal Protrusion With External Minicrush for Treatment of Complex Coronary Bifurcation · recruiting
- NCT06720935 — Use of Coils During Percutaneous Coronary Intervention · completed
- NCT05713201 — Outcomes After PCI of the Aneurysmatic Right Coronary Artery · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05782738 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by San Luigi Gonzaga Hospital
- Last refreshed: 19 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05782738.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing