NCT05781529

Injectable Platelets Rich Fibrin Versus Hyaluronic Acid for Alveolar Ridge Preservation

Completed NA Last updated 23 March 2023

What this trial tests

NA trial testing Alveolar ridge augmentation with injectable platelets rich fibrin in Alveolar Ridge Enlargement in 36 participants. Completed in 31 August 2021.

Timeline

6 March 2019

Primary endpoint
16 July 2021

31 August 2021

Quick facts

Lead sponsor	Ain Shams University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	36
Start date	6 March 2019
Primary completion	16 July 2021
Estimated completion	31 August 2021
Sites	2 locations across Egypt

Drugs / interventions tested

• Alveolar ridge augmentation with injectable platelets rich fibrin
• Alveolar ridge augmentation with hyaluronic acid
• Alveolar ridge augmentation with xenograft

Conditions studied

• Alveolar Ridge Enlargement — all drugs for Alveolar Ridge Enlargement →

Sponsor

Ain Shams University

Who can join

Adults 20 to 45, any sex, with Alveolar Ridge Enlargement. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Thirty-six patients (19 females and 17 males) that required implant placement in esthetic zone participated in this study and were blindly allocated 12 patients per group, all patients had ARP either with I-PRF with xenograft, HA with xenograft or xenograft alone, the sockets were sealed with free gingival graft harvested from the palate.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Injectable platelet rich fibrin versus hyaluronic acid with bovine derived xenograft for alveolar ridge preservation. A randomized controlled clinical trial with histomorphometric analysis.
   Abaza G, Abdel Gaber HK, Afifi NS, Adel-Khattab D. · · 2024 · cited 15× · PMID 37905704 · DOI 10.1111/cid.13289