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NCT05781373
Effect of Intraoperative PEEP Individualization According to Driving Pressure in Major Abdominal Surgery
NA trial testing Peep individualization in Mechanical Ventilation Complication in 100 participants. Status unknown.
30 April 2024
Quick facts
| Lead sponsor | Mongi Slim Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 100 |
| Start date | 1 April 2023 |
| Primary completion | 30 April 2024 |
| Estimated completion | 30 June 2024 |
Drugs / interventions tested
- Peep individualization
Conditions studied
- Mechanical Ventilation Complication — all drugs for Mechanical Ventilation Complication →
Sponsor
Mongi Slim Hospital
Who can join
18 and older, any sex, with Mechanical Ventilation Complication. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this prospective, randomized trial, including patients scheduled for a major open or laparoscopic abdominal surgery (duration \>2 hours) under general anesthesia , the investigators will compare 2 strategies of protective mechanical ventilation: a fixed intraoperative PEEP of 6 cmH2O and an individualized intraoperative PEEP according to the driving pressure.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05781373
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Mechanical Ventilation Complication
Currently open trials in the same condition.
- NCT06921655 — Targeting prEssure-Muscle-index to Avoid Ventilatory Over-Assistance During Pressure Support Ventilation · NA · recruiting
- NCT07207772 — EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery · NA · recruiting
- NCT07182851 — Prevalence of Pain in Mechanically Ventilated Patients in Intensive Care Units · recruiting
- NCT06575530 — Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients · Phase 4 · recruiting
- NCT06592144 — TESTO-TRIAL: Use of Testosterone in Critically Ill Patients · Phase 4 · active not recruiting
Other Mongi Slim Hospital trials
Trials by the same sponsor.
- NCT06511427 — Difficult Airways Scores Validation Difficult Laryngoscopy and Mask Ventilation: Prospective and Evaluative Study · not yet recruiting
- NCT06676865 — Preoperative Prediction of Difficult Laryngoscopy in Diabetic Patients: Importance of the Palm Print Test · completed
- NCT06444737 — Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia · NA · recruiting
- NCT06203353 — Evaluation of the Diaphragm Performance During Weaning From Mechanical Ventilation · unknown
- NCT06622096 — Evaluation of Lab Exams Accuracy in the Intensive Care Unit · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05781373 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mongi Slim Hospital
- Last refreshed: 23 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05781373.
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