Last reviewed · How we verify
NCT05780957
Multi-Cancer Early Detection (MCED) of Firefighters
trial testing MCED in Cancer in 2,000 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Vincere Cancer Center |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 2,000 |
| Start date | 21 March 2023 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2030 |
| Sites | 1 location across United States |
Drugs / interventions tested
- MCED
Conditions studied
- Cancer — all drugs for Cancer →
Sponsor
Vincere Cancer Center
Who can join
18 and older, any sex, with Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is an an observational prospective cohort research study to explore the performance of new blood and urine tests for the early detection of cancer among firefighters.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Transforming cancer screening: the potential of multi-cancer early detection (MCED) technologies.
Imai M, Nakamura Y, Yoshino T. · · 2025 · cited 15× · PMID 39799530 · DOI 10.1007/s10147-025-02694-5 -
Cancer Screening: Present Recommendations, the Development of Multi-Cancer Early Development Tests, and the Prospect of Universal Cancer Screening.
Galeș LN, Păun MA, Anghel RM, Trifănescu OG. · · 2024 · cited 9× · PMID 38539525 · DOI 10.3390/cancers16061191 -
Multicancer Early Detection Tests: A State-of-the-Art Review for Otolaryngologists.
Kennedy E, Durm G, Farlow JL. · · 2024 · cited 2× · PMID 39463807 · DOI 10.1002/oto2.70040
Verify or expand the search:
- PubMed search for NCT05780957
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Vincere Cancer Center trials
Trials by the same sponsor.
- NCT06173843 — Occupational Exposures Among Firefighters · recruiting
- NCT05954299 — Vincere Biobank Research Protocol · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05780957 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Vincere Cancer Center
- Last refreshed: 5 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05780957.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing