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NCT05780476: VirtualCare
A Novel VIRTUAL Reality Intervention for CAREgivers of People With Dementia (VirtualCare)
NA trial testing Psychoeducation in Caregiver Burden in 127 participants. Completed in 31 July 2025.
27 February 2025
Quick facts
| Lead sponsor | IRCCS Centro San Giovanni di Dio Fatebenefratelli |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 127 |
| Start date | 27 October 2022 |
| Primary completion | 27 February 2025 |
| Estimated completion | 31 July 2025 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Psychoeducation
- Psychoeducation + virtual reality
Conditions studied
- Caregiver Burden — all drugs for Caregiver Burden →
Sponsor
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Who can join
18 and older, any sex, with Caregiver Burden. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial aims to explore if a virtual reality experience increases the beneficial effect of psychoeducational programs in informal caregivers of people with mild-to-moderate Alzheimer's disease. This study will test changes in psychological distress and neural activity in brain systems that regulate stress and empathic care. Participants will be randomized into two arms: the control group will participate in an online psychoeducational intervention, while the experimental group will participate in the psychoeducational intervention combined with virtual reality.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Virtual Reality Combined With Psychoeducation to Improve Emotional Well-Being in Informal Caregivers of Alzheimer's Disease Patients: Rationale and Study Design of a Randomized Controlled Trial.
Festari C, Bonomini C, Rosini S, Gattuso M, et al · · 2024 · cited 6× · PMID 39267224 · DOI 10.1002/gps.6145 -
Virtual Reality-Based Psychoeducation for Dementia Caregivers: The Link between Caregivers' Characteristics and Their Sense of Presence.
Morganti F, Gattuso M, Singh Solorzano C, Bonomini C, et al · · 2024 · cited 4× · PMID 39335348 · DOI 10.3390/brainsci14090852 -
The psychological impact of the disclosure of the diagnosis of Alzheimer's disease on informal caregivers.
Singh Solorzano C, Bonomini C, Rosini S, Passeggia I, et al · · 2025 · cited 3× · PMID 40908671 · DOI 10.1002/alz.70412
Verify or expand the search:
- PubMed search for NCT05780476
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Caregiver Burden
Currently open trials in the same condition.
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- NCT07168577 — Sleep Quality and Caregiver Burden in Children With Cerebral Palsy · recruiting
- NCT07528261 — ACT Group for Stroke Caregivers · NA · recruiting
- NCT06367556 — Emotion and Symptom-Focused Engagement (EASE) for Caregivers · NA · recruiting
Other IRCCS Centro San Giovanni di Dio Fatebenefratelli trials
Trials by the same sponsor.
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- NCT06989944 — Physical Activity-based Intervention in Depressed Patients: Clinical, Neurophysiological, Epigenetic and Metabolic Corre · NA · active not recruiting
- NCT06657274 — EARLY-COGN^3 - Smart Digital Solutions for EARLY Treatment of COGnitive Disability: a Neuropsychological, Neurophysiolog · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05780476 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS Centro San Giovanni di Dio Fatebenefratelli
- Last refreshed: 1 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05780476.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing