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Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases
The aim of this study is to explore the therapeutic effect of Quintuple method in the treatment of patients with multiple and refractory liver metastases from colorectal cancer. A randomized single-arm clinical trial was conducted.The intervention group was treated with single SOX chemotherapy, SOX chemotherapy combined with cetuximab targeted therapy, SOX chemotherapy combined with low-dose cetuximab targeted therapy combined with three-drug regimen（Quintuple method）, and the RECIST 1.1 solid tumor evaluation criteria were used to assess the disease.
Details
| Lead sponsor | Liaoning Cancer Hospital & Institute |
|---|---|
| Phase | PHASE2 |
| Status | UNKNOWN |
| Enrolment | 100 |
| Start date | Wed Mar 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sat Mar 15 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- For Patients With Colorectal Cancer Liver Metastases Who Were Not Able to Curative Surgical Resection.Focused on the Treatment Effect With the Quintuple Method
Interventions
- Oxaliplatin
- S1
- Cetuximab
- Metronidazole
- Vitamin A
- Folic acid
Countries
China