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NCT05774652
LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers
NA trial testing Lifestyle intervention Dietary advise and/or advise on physical activity in Obesity in 301 participants. Currently enrolling.
1 December 2025
Quick facts
| Lead sponsor | Odense University Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 301 |
| Start date | 26 October 2023 |
| Primary completion | 1 December 2025 |
| Estimated completion | 1 March 2026 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Lifestyle intervention Dietary advise and/or advise on physical activity
Conditions studied
- Obesity — all drugs for Obesity →
- Life Style, Healthy — all drugs for Life Style, Healthy →
- Follow-up — all drugs for Follow-up →
- Gestational Weight Gain — all drugs for Gestational Weight Gain →
Sponsor
Odense University Hospital
Who can join
Adults 13 to 65, any sex, with Obesity or Life Style, Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study is a follow-up of a Randomized Controlled Trial (RCT) performed in 2007-10 - the "Lifestyle in Pregnancy" LiP study. The LiP study included 360 pregnant women with BMI ≥30 kg/m2 from Odense University Hospital and Aarhus University Hospital. The women were randomized to intervention with low-calorie diet and physical activity from gestational age 10-14 in pregnancy and until delivery - or to a standard care control group. The objective of the LiPO-Teen project is to perform a clinical follow-up study of the eligible 301 mothers who completed the trial until delivery with a liveborn child, and their 14 year-old offspring. The overall ambition is to understand whether lifestyle intervention in pregnancy prevents obesity and its complications across generations, with a specific focus on modifiable factors.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Impact of maternal fasting blood glucose in pregnancy on body composition, anthropometric, and metabolic outcomes in newborns and 3-Year-Old offspring: results from the lifestyle in pregnancy and offspring study.
Luef BM, Stentebjerg LL, Tanvig MH, Aalders J, et al · · 2026 · PMID 41612293 · DOI 10.1186/s12884-026-08692-3 -
Study protocol for a 15-year follow-up of a randomized controlled trial on lifestyle intervention in pregnancy: assessing long-term effects on body composition, metabolic traits, and mental health in mothers and offspring.
Luef BM, Jensen NH, Knorr S, Kristensen K, et al · · 2026 · PMID 41535891 · DOI 10.1186/s13063-025-09418-0
Verify or expand the search:
- PubMed search for NCT05774652
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05774652 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Odense University Hospital
- Last refreshed: 19 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05774652.
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