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NCT05771467

Evaluation of Retinal Microvascular Change That May Develop in After Open Globe Injury

Completed Results posted Last updated 16 January 2025
What this trial tests

trial testing Comprehensive Ophthalmologic Examination in Eye Injury Trauma in 100 participants. Completed in 2 September 2024.

Timeline
2 March 2024
Primary endpoint
2 September 2024
2 September 2024

Quick facts

Lead sponsorAkdeniz University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment100
Start date2 March 2024
Primary completion2 September 2024
Estimated completion2 September 2024
Sites2 locations across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Akdeniz University

Who can join

18 and older, any sex, with Eye Injury Trauma. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Corneal Thickness Primary · 10 minutes

Corneal thickness in mikrometer value

GroupValue95% CI
Trauma Group542.23± 27.47
Control Group546.16± 46.03
Total Group544.32± 35.3
Anterior Chamber Volume Primary · 10 minutes

Anterior chamber volume in mm3

GroupValue95% CI
Trauma Group177.97± 28.46
Control Group165.9± 26.73
Anterior Chamber Depth Primary · 10 minutes

Anterior chamber depth in mm

GroupValue95% CI
Trauma Group2.93± 0.25
Control Group3.05± 0.29
Anterior Chamber Angle Primary · 10 minutes

Anterior chamber angle in degree

GroupValue95% CI
Trauma Group38.87± 6.42
Control Group37.8± 4.74
Lens Power Primary · 10 minutes

in diopters

GroupValue95% CI
Trauma Group20.98± 0.35
Control Group20.26± 0.44
Steep Keratometry Primary · 10 minutes

in Diopters measured with pentacam

GroupValue95% CI
Trauma Group44.22± 1.64
Control Group44.57± 1.82
Tonometry Primary · 10 minutes

Intraocular pressure measurement in mmHg

GroupValue95% CI
Trauma Group14.74± 0.49
Control Group15.78± 0.35
Axial Length Primary · 10 minutes

Axial length in mm

GroupValue95% CI
Trauma Group23.86± 0.94
Control Group23.36± 0.72
Optic Nerve Head Vessel Density Primary · 10 minutes

Optic nerve head vessel density assessed with optical coherence tomography angiography

GroupValue95% CI
Trauma Group23.22± 5.2
Control Group25.2± 4.4
Choriocapillaris Flow Area Primary · 10 minutes

Choriocapillaris flow area assessed with optical coherence tomography angiography

GroupValue95% CI
Trauma Group36.88± 1.52
Control Group36.53± 1.89
Subfoveal Central Macular Thickness Primary · 10 minutes

Subfoveal central macular thickness assessed with optical coherence tomography

GroupValue95% CI
Trauma Group321.42± 24.52
Control Group311.57± 31.13

Sponsor's own description

The aim of this study is to evaluate posterior segment changes in the non-traumatic eye after open globe injury.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other trials of Comprehensive Ophthalmologic Examination

Trials testing the same drug.

Other Akdeniz University trials

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Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05771467.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing