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NCT05761535: BigImAGING
Big Data and Genomic Imaging for the Development of Biomarkers and Nanovector Drugs Innovative for Diagnosis and Therapy of Inflammatory Processes in Dementia
trial testing Magnetic Resonance (MR) and positron emission tomograph (PET) imaging analyses in Neurodegenerative Diseases in 137 participants. Completed in 30 June 2023.
28 February 2023
Quick facts
| Lead sponsor | IRCCS SYNLAB SDN |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 137 |
| Start date | 17 June 2020 |
| Primary completion | 28 February 2023 |
| Estimated completion | 30 June 2023 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Magnetic Resonance (MR) and positron emission tomograph (PET) imaging analyses
Conditions studied
- Neurodegenerative Diseases — all drugs for Neurodegenerative Diseases →
Sponsor
IRCCS SYNLAB SDN
Who can join
Adults 18 to 85, any sex, with Neurodegenerative Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The correlation between data obtained by "imaging" in patients with neurodegenerative diseases characterized by inflammation and the presence in the peripheral blood of the same patients "biopsies liquid biopsies" of specific circulating nucleic acids, could enable the development of methods and algorithms capable of identifying novel biomarkers that serve as targets for the development of probes diagnostics and therapeutics. This is the context for the project idea, which is aimed at developing development of a performant multi parameter system capable of identifying novel biomarkers of microglial polarization that can be used for diagnostic and prognostic purposes in determining the staging/progression of neurodegenerative disease
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05761535
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other IRCCS SYNLAB SDN trials
Trials by the same sponsor.
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- NCT06878534 — Observational Study Analysing the Transcriptome and Mutational Status of Thyroid Carcinomas of Follicular Origin with Di · recruiting
- NCT05767489 — Study of Brain Anatomo-functional Substrates Related to the Use of Human Tool by Means of Simultaneous Acquisition of Ma · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05761535 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS SYNLAB SDN
- Last refreshed: 25 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05761535.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing