Who is sponsoring NCT05759091?

NCT05759091 is sponsored by Alexandria University.

What drugs are being tested in NCT05759091?

Interventions in NCT05759091: cognitive defusion techniques.

What condition does NCT05759091 study?

NCT05759091 studies Schizophrenia; Psychosis, Nurse's Role, Delusions.

Is NCT05759091 still recruiting?

NCT05759091 is currently completed. Last updated 19 July 2023.

Last reviewed 2023-07-19 · How we verify

NCT05759091

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Applying Cognitive Defusion Techniques on Mindful Awareness, Cognitive Fusion and Believability of Delusions Among Clients With Schizophrenia

Completed NA Last updated 19 July 2023

What this trial tests

NA trial testing cognitive defusion techniques in Schizophrenia; Psychosis in 70 participants. Completed in 20 January 2023.

Timeline

10 September 2022

Primary endpoint
20 November 2022

20 January 2023

Quick facts

Lead sponsor	Alexandria University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	70
Start date	10 September 2022
Primary completion	20 November 2022
Estimated completion	20 January 2023
Sites	1 location across Egypt

Drugs / interventions tested

cognitive defusion techniques

Conditions studied

Schizophrenia; Psychosis — all drugs for Schizophrenia; Psychosis →
Nurse's Role — all drugs for Nurse's Role →
Delusions — all drugs for Delusions →

Sponsor

Alexandria University

Who can join

Eligibility, male only, with Schizophrenia; Psychosis or Nurse's Role. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Schizophrenia causes hallucinations, delusions, and disorganized thinking, resulting in decreased functioning and lifelong therapy.Delusion believability is the degree of belief in the truth of one's subjective experiences as representations of reality. It was unpleasant, typically accompanied by a suspicious, strange tension. Delusional belief is seen as a means of resolving tension and conflict in cognition and experience. Previous studies have shown that cognitive defusion strategies help people become more aware of their surroundings, accept their thoughts and feelings, and become more psychologically adjustable. defusion is crucial in reducing medication-resistant psychotic symptoms such delusions in schizophrenia patients. Therefore, this study aimed to investigate the effects of cognitive defusion techniques on psychological flexibility, mindful awareness, cognitive fusion, and believability of delusions among clients with schizophrenia. Research Hypothesizes * Clients who participated in cognitive defusion techniques had more psychological flexibility and mindful awareness than the control group. * Clients who participated in cognitive defusion techniques had less cognitive fusion and delusional believability than the control group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of applying nursing-based cognitive defusion techniques on mindful awareness, cognitive fusion, and believability of delusions among clients with schizophrenia: a randomized control trial.
El-Ashry AM, Abd Elhay ES, Taha SM, Khedr MA, et al · · 2024 · cited 3× · PMID 38736628 · DOI 10.3389/fpsyt.2024.1369160

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05759091 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Alexandria University
Last refreshed: 19 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05759091.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing