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NCT05758129

Association Between PM2.5 Exposure and Ferroptosis in Seizures Patients

Status unknown Last updated 7 March 2023
What this trial tests

trial in Exposure to Polluted Air in 60 participants. Status unknown.

Timeline
1 December 2022
Primary endpoint
10 March 2023
25 March 2023

Quick facts

Lead sponsorAffiliated Hospital of Jiangnan University
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment60
Start date1 December 2022
Primary completion10 March 2023
Estimated completion25 March 2023
Sites1 location across China

Conditions studied

Sponsor

Affiliated Hospital of Jiangnan University

Who can join

Adults 6 to 18, any sex, with Exposure to Polluted Air. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This cohort study aims to discover the possible effects of PM2.5 exposures on the Nrf2- dependent ferroptosis pathway in seizure patients. This observational cohort's main question is whether PM2.5 exposures will affect the Nrf2- dependent ferroptosis pathway in seizure patients. Participants will be divided into two groups: the control group and the air pollution to detect the biomarkers of the Nrf2- dependent ferroptosis pathway in seizure patients

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. In defence of ferroptosis.
    Alves F, Lane D, Nguyen TPM, Bush AI, et al · · 2025 · cited 75× · PMID 39746918 · DOI 10.1038/s41392-024-02088-5

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Other Affiliated Hospital of Jiangnan University trials

Trials by the same sponsor.

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