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NCT05755633

Role of Day +60 WT1 Assessment on Bone Marrow in Predicting Relapse and Mortality After Allogeneic Stem Cell Transplantation

Completed Last updated 6 March 2023
What this trial tests

trial in Assessment of the WT1 Expression Level on Bone Marrow Samples Collected at Day +60 After Allogeneic Stem in 50 participants. Completed in 31 December 2021.

Timeline
22 April 2021
Primary endpoint
31 December 2021
31 December 2021

Quick facts

Lead sponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS
StatusCompleted
Study typeOBSERVATIONAL
Enrollment50
Start date22 April 2021
Primary completion31 December 2021
Estimated completion31 December 2021
Sites1 location across Italy

Conditions studied

Sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Who can join

Adults 18 to 100, any sex, with Assessment of the WT1 Expression Level on Bone Marrow Samples Collected at Day +60 After Allogeneic Stem. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The rationale of this study is to determine if an association exists between WT1 expression and relapse occurrence in patients with acute myeloid leukemia submitted to allogeneic stem cell transplantation. In particular, we want to studied WT1 expression level on bone marrow samples of day +60 in terms of predicting power on relapse incidence so as to determine a cut-off value for identify high risk patients.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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