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NCT05753332

Association Between PM2.5 and Ferroptosis

Status unknown Last updated 3 March 2023
What this trial tests

trial in Exposure to Polluted Air in 60 participants. Status unknown.

Timeline
1 December 2022
Primary endpoint
25 February 2023
1 March 2023

Quick facts

Lead sponsorNorthern Jiangsu People's Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment60
Start date1 December 2022
Primary completion25 February 2023
Estimated completion1 March 2023
Sites1 location across China

Conditions studied

Sponsor

Northern Jiangsu People's Hospital

Who can join

18 and older, any sex, with Exposure to Polluted Air. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This cohort study aims to discover the possible effects of PM2.5 exposures on the Nrf2- dependent ferroptosis pathway. This observational cohort's main question is whether PM2.5 exposures will affect the Nrf2- dependent ferroptosis pathway. Participants will be divided into two groups: the control group and the air pollution to detect the biomarkers of the Nrf2- dependent ferroptosis pathway.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. In defence of ferroptosis.
    Alves F, Lane D, Nguyen TPM, Bush AI, et al · · 2025 · cited 75× · PMID 39746918 · DOI 10.1038/s41392-024-02088-5

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Other Northern Jiangsu People's Hospital trials

Trials by the same sponsor.

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