Last reviewed · How we verify
NCT05752799
Evaluation of the Stress Response in Bariatric Surgery With and Without the Use of Opioids
NA trial testing Opioid Free Anaesthesia in Opioid Use, Unspecified in 70 participants. Status unknown.
28 February 2025
Quick facts
| Lead sponsor | G.Gennimatas General Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 70 |
| Start date | 1 January 2023 |
| Primary completion | 28 February 2025 |
| Estimated completion | 1 June 2025 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- Opioid Free Anaesthesia — full drug profile →
- Opioid based anesthesia — full drug profile →
Conditions studied
- Opioid Use, Unspecified — all drugs for Opioid Use, Unspecified →
- Bariatric Surgery Candidate — all drugs for Bariatric Surgery Candidate →
Sponsor
G.Gennimatas General Hospital
Who can join
Adults 18 to 75, any sex, with Opioid Use, Unspecified or Bariatric Surgery Candidate. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to compare Opioid Free and Opioid Based Anaesthesia in patients undergoing sleeve gastrectomy. The main questions it aims to answer are: * Will the total dose of intraoperative opioid be reduced? * Will there be difference in pain scores between groups? Participants will be managed with the Nociceptive Level Index algorithm to guide intraoperative analgesia. The Opioid Free Anaesthesia Group will be administered the Multimix infusion (Magnesium sulfate, dexmedetomidine, ketamine). The Opioid Based Anaesthesia Group will receive fentanyl as a bolus dose and remifentanil infusion. Rescue fentanyl bolused will be injected as appropriate according to nociceptive level (NOL) values.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05752799
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Opioid Free Anaesthesia
Trials testing the same drug.
- NCT06714981 — Hemodynamics Stability During Opioid Free Anesthesia for Patients with Obesity · NA · completed
Other recruiting trials for Opioid Use, Unspecified
Currently open trials in the same condition.
- NCT06291363 — Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception. · Phase 4 · recruiting
- NCT05662371 — Influence of Nociception Level Monitor (NOL) Guided Analgesic Delivery on Robot-assisted Colorectal Surgery · NA · recruiting
- NCT03923374 — Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes · recruiting
Other G.Gennimatas General Hospital trials
Trials by the same sponsor.
- NCT06917755 — The Impact of Immersive Virtual Reality Training in Thyroid Surgery · NA · recruiting
- NCT04780438 — Dapagliflozin to Prevent Atrial Fibrillation Recurrence After Transcatheter Pulmonary Venous Isolation. · EARLY_PHASE1 · unknown
- NCT04806633 — Dapagliflozin to Prevent the Incidence of Contrast Induced Nephropathy After Heart Catheterization and Percutaneous Coro · EARLY_PHASE1 · unknown
- NCT04756817 — Immunogenicity of the BNT162b2 Covid-19 Vaccine in Elderly People Aged 85 and Older in Greece · completed
- NCT03573869 — Atrial FIbrillation Treatment With Cryoballoon in Heart failurE (AFICHE) · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05752799 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by G.Gennimatas General Hospital
- Last refreshed: 19 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05752799.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing