Last reviewed · How we verify
NCT05747339
A Clinical Study on the Efficacy and Mechanism of Tumor Treatment Vaccine (TTV) for Recurrent and Refractory Advanced Solid Tumors
NA trial testing tumor treatment vaccine injection in Solid Tumors, Adult in 50 participants. Status unknown.
31 December 2024
Quick facts
| Lead sponsor | Wuxi People's Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 7 June 2023 |
| Primary completion | 31 December 2024 |
| Estimated completion | 31 December 2024 |
Drugs / interventions tested
- tumor treatment vaccine injection — full drug profile →
Conditions studied
- Solid Tumors, Adult — all drugs for Solid Tumors, Adult →
Sponsor
Wuxi People's Hospital
Who can join
Adults 18 to 75, any sex, with Solid Tumors, Adult. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a study of the clinical efficacy and mechanism study of tumor treatment vaccine (TTV, also known as Neo-BCV) in patients with recurrent and refractory advanced solid tumors.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Neo-BCV: A Novel Bacterial Complex Vaccine Reshaping the Gut Microbiota to Enhance the Antitumor Immune Response.
Yang H, Zhu H, Zhu Z, Man L, et al · · 2026 · PMID 42042786 · DOI 10.3390/vaccines14040310 -
Neo-BCV: A Novel Bacterial Liquid Complex Vaccine for Enhancing Dendritic Cell-Mediated Immune Responses Against Lung Cancer.
Zhu Z, Chu Z, Fei F, Wu C, et al · · 2025 · PMID 39852843 · DOI 10.3390/vaccines13010064
Verify or expand the search:
- PubMed search for NCT05747339
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Solid Tumors, Adult
Currently open trials in the same condition.
- NCT07396584 — HMPL-A580 in Participants With Advanced or Metastatic Solid Tumor · Phase 1, PHASE2 · recruiting
- NCT07417189 — A Phase I/II Study of ABSK141 in Patients With Advanced Solid Tumors ( ABSK141-101 ) · Phase 1, PHASE2 · recruiting
- NCT07228247 — A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors · Phase 1, PHASE2 · recruiting
- NCT06504368 — Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors · Phase 1 · recruiting
- NCT05861895 — HF158K1 in Patients With HER-2 Expressing Advanced Solid Tumors · Phase 1 · recruiting
Other Wuxi People's Hospital trials
Trials by the same sponsor.
- NCT06430502 — Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced · NA · recruiting
- NCT06240767 — Clinical Study on the Treatment of Advanced Recurrent Tumors With Anticancer Mouse Characteristic Human Neutrophils · Phase 1 · unknown
- NCT06404528 — Low-dose Chemotherapy Under Hypoglycaemia for the Treatment of Relapsed Refractory Advanced Solid Tumours · NA · recruiting
- NCT06430515 — The Clinical Efficacy and Safety of Intratumoral Injection of Chemotherapy for Advanced Solid Tumors · NA · recruiting
- NCT05523050 — Active Surgical Intervention on Crohn's Disease · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05747339 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wuxi People's Hospital
- Last refreshed: 13 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05747339.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing