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NCT05747053: STAART
Personalization of Immunosuppressive Treatment for Organ Transplant Recipients
trial testing AlloSure in Kidney Injury in 105 participants. Terminated before completion.
8 December 2022
Quick facts
| Lead sponsor | George Washington University |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 105 |
| Start date | 1 October 2020 |
| Primary completion | 8 December 2022 |
| Estimated completion | 8 December 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- AlloSure
- PAXGene
Conditions studied
- Kidney Injury — all drugs for Kidney Injury →
- Kidney Failure — all drugs for Kidney Failure →
- Kidney Failure, Chronic — all drugs for Kidney Failure, Chronic →
- Kidney Failure, Acute — all drugs for Kidney Failure, Acute →
Sponsor
George Washington University
Who can join
Adults 18 to 80, any sex, with Kidney Injury or Kidney Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Long-term graft failure rates continue to be unacceptably high despite the development of immunosuppressive drugs, underscoring the unmet need for robust prognostic biomarkers of allograft injury and failure. While rates of acute rejection (AR) continue to decrease, it remains the strongest predictor of long-term allograft survival, and so having a better understanding of factors predicting AR may contribute to more individualized patient care. Selecting optimum immunosuppressive dosage is another factor in personalizing kidney care. This project will study two areas of individualized kidney care: 1) assessing rejection by surveillance testing utilizing AlloSure, 2) developing an algorithm to select optimum immunosuppressive medication dosage.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05747053
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of AlloSure
Trials testing the same drug.
- NCT04601155 — Transition of Renal Patients Using AlloSure Into Community Kidney Care · completed
- NCT04566055 — Assessing AlloSure Dd-cfDNA Monitoring Insights of Renal Allografts With Longitudinal Surveillance · unknown
Other recruiting trials for Kidney Injury
Currently open trials in the same condition.
- NCT06585722 — Association Between Venous Excess Ultrasound Grading System and Acute Kidney Injury in the ICU Population · recruiting
- NCT05696444 — Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO) · NA · active not recruiting
- NCT06781476 — Evaluation of Urinary Biomarkers Trend in Preterm Very Low Birth Weight Infants · recruiting
- NCT05283512 — Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanc · NA · recruiting
- NCT04902846 — Immune Checkpoint Inhibitors Nephrotoxicity · recruiting
Other George Washington University trials
Trials by the same sponsor.
- NCT07279129 — Decision Support Tool to Integrate PrEP Into Emergency Departments · Phase 1 · not yet recruiting
- NCT07524309 — Self-Help Plus Pilot Study, Colombia: Train2Care · NA · not yet recruiting
- NCT07249008 — NSS Grocery Store Brazil · NA · recruiting
- NCT07000513 — HIV Self-Testing and Long-Acting Injectables for HIV Treatment and Prevention Among Commercial Minibus Drivers (I-TEST L · Phase 4 · not yet recruiting
- NCT07079306 — ChatGPT-Supported Text Messaging Program for Smoking Cessation · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05747053 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by George Washington University
- Last refreshed: 26 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05747053.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing