Who is sponsoring NCT05747027?

NCT05747027 is sponsored by Endeavor Health.

What drugs are being tested in NCT05747027?

Interventions in NCT05747027: Laparoscopic abdominal ventral rectopexy, Transvaginal sacrospinous rectopexy.

What condition does NCT05747027 study?

NCT05747027 studies Obstructed Defecation, Pelvic Organ Prolapse.

Is NCT05747027 still recruiting?

NCT05747027 is currently terminated. Last updated 15 July 2025.

Are results published for NCT05747027?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2025-07-15 · How we verify

NCT05747027: PROD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prospective Randomized Controlled Trial of Obstructed Defecation Surgery

Terminated NA Results posted Last updated 15 July 2025

What this trial tests

NA trial testing Laparoscopic abdominal ventral rectopexy in Obstructed Defecation in 15 participants. Terminated before completion.

Timeline

16 May 2024

Primary endpoint
30 May 2025

30 May 2025

Quick facts

Lead sponsor	Endeavor Health
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	15
Start date	16 May 2024
Primary completion	30 May 2025
Estimated completion	30 May 2025
Sites	2 locations across United States

Drugs / interventions tested

Laparoscopic abdominal ventral rectopexy
Transvaginal sacrospinous rectopexy

Conditions studied

Obstructed Defecation — all drugs for Obstructed Defecation →
Pelvic Organ Prolapse — all drugs for Pelvic Organ Prolapse →

Sponsor

Endeavor Health — full company profile →

Who can join

Adults 18 to 80, female only, with Obstructed Defecation or Pelvic Organ Prolapse. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Obstructive defecatory syndrome (ODS) or inability to completely empty bowel is characterized by a combination of straining, incomplete evacuation, and the use of digital manipulation with bowel movement. This is a common condition with estimated incidence of 15-20% in the adult female population. Laparoscopic abdominal ventral rectopexy is an established surgical technique aimed at restoring rectal support in women with this condition. It is the most common surgery used nowadays to treat ODS. Transvaginal sacrospinous rectopexy, is an innovative procedure which has been shown to be safe and effective in the treatment of stool entrapment. Currently it is unknown whether one of the procedures mentioned is superior to the other regarding surgical outcomes and patient experience. The purpose of this research is to compare the outcomes of these two procedures considering their efficacy to improve symptoms. During the study, participants will be randomized to undergo one of two procedures for treatment of inability to completely empty their bowel and/or rectal prolapse: 1) laparoscopic abdominal ventral rectopexy; 2) transvaginal sacrospinous rectopexy. Following the procedure, participants will be asked to return to the office for a follow-up visit 2-weeks, 2-, 12- and 24-months after the surgery. During each follow-up visit participants will undergo symptom evaluation, pelvic exam and transvaginal pelvic ultrasound to evaluate surgical success.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other Endeavor Health trials

Trials by the same sponsor.

NCT06258785 — Effect of Tizanidine on Postoperative Urinary Retention After Sacrospinous Suspension · Phase 3 · completed
NCT06279195 — Phenotyping of Idiopathic Pelvic Pain With Real-time Uterine Imaging and Relugolix-Combination Therapy Treatment · Phase 2 · withdrawn
NCT05921149 — Fasting Mimicking Diet (FMD) in Conjunction With Chemotherapy in Advanced Ovarian Cancer · NA · not yet recruiting
NCT06062875 — Effects of TNF Blockade on Human BPH/LUTS · Phase 2 · recruiting
NCT06007547 — Prophylactic Minimally Invasive Surfactant Evaluation · Phase 4 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05747027 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Endeavor Health
Last refreshed: 15 July 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05747027.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing