Last reviewed · How we verify
NCT05746819: MRIA
An MRI Ancillary Study of a Malaria Fever Investigation
trial testing Aggressive antipyretics therapy of fever vs usual care in the Malaria RCT study in Brain Injuries in 181 participants. Completed in 31 March 2024.
31 August 2023
Quick facts
| Lead sponsor | University of Rochester |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 181 |
| Start date | 2 January 2021 |
| Primary completion | 31 August 2023 |
| Estimated completion | 31 March 2024 |
| Sites | 2 locations across Malawi, Zambia |
Drugs / interventions tested
- Aggressive antipyretics therapy of fever vs usual care in the Malaria RCT study
Conditions studied
- Brain Injuries — all drugs for Brain Injuries →
- Malaria — all drugs for Malaria →
- MRI Imaging — all drugs for MRI Imaging →
- Neurocognitive Deficits — all drugs for Neurocognitive Deficits →
Sponsor
University of Rochester
Who can join
Adults 2 to 12, any sex, with Brain Injuries or Malaria. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will seek consent from parents of children enrolled in the Malaria FEVER study to obtain neuroimaging and 12-month neuropsychiatric outcomes data and kidney function on their child. The imaging and evaluations for this observational study will occur after the child has recovered from the acute malaria infection and has otherwise completed the RCT intervention and safety evaluations.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05746819
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Brain Injuries
Currently open trials in the same condition.
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- NCT06511804 — Correlation Between Noninvasive Blood Vessel Functionality Parameters and Cerebral Hemodynamics in Neurocritical Care Pa · recruiting
- NCT06863025 — Effects of Neurofeedback Training on Attentional Deficits in Patients With Acquired Brain Injury · NA · active not recruiting
- NCT06571032 — Electroencephalography in the Management of Neuroelectric Stimulation in Patients With Severe Traumatic Brain Injuries · recruiting
Other University of Rochester trials
Trials by the same sponsor.
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- NCT05744869 — SBAT for Health Equity · NA · not yet recruiting
- NCT06052956 — Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses · Phase 2 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05746819 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Rochester
- Last refreshed: 15 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05746819.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing